Adult Clinical Trials

Gynecological Cancers - Ovarian cancer and cancers of the female organs

If you need additional information about any of the trials listed or would like to inquire about other open trials, please contact the Gynecology (GYN) Clinical Trials Office at 919.555.3780.

14 trials identified.

A Phase III Randomized Controlled Clinical Trial of Carboplatin and Paclitaxel (or Gemcitabine) Alone or in Combination with Bevacizumab Followed by Bevacizumab and Secondary Cytoreductive Surgery in Platinum-Sensitive, Recurrent Ovarian, Fallopian Tube and Peritoneal Primary Cancer
Phase: Phase III
Sponsor: Cooperative Group Initiated
Principal Investigator: Angeles Secord
Contact: GYN Oncology Clinical Trials
Phone: 919.684.3780
Reference Number: 00007487
View this trial at ClinicalTrials.gov

Cervical Cancer Detection Using Optical Spectroscopy
Phase: N/A
Sponsor: PI initiated
Principal Investigator: Nimmi Ramanujam
Contact: Marlee Junker
Phone: 919.660.8446
Reference Number: 00008173
View this trial at ClinicalTrials.gov

Tissue and Data Acquisition Activity for the Study of Gynecologic Disease
Phase: Other
Sponsor: Federal Government initiated
Principal Investigator: Laura Havrilesky
Contact: Debra Davis, RN
Phone: 919.684.6125
Reference Number: 00013703
View this trial at ClinicalTrials.gov

GOG 0264: A Randomized Phase II Trial of Paclitaxel and Carboplatin vs. BLeomycin, Etoposide, and Cisplatin for Newly Diagnosed Advanced Stage and Recurrent Chemonaive Sex Cord-Stromal Tumors of The Ovary
Phase: Phase II
Sponsor: Cooperative Group Initiated
Principal Investigator: Angeles Secord
Contact: GYN Oncology Clinical Trials
Phone: 919.684.3780
Reference Number: 00022731
View this trial at ClinicalTrials.gov

A Randomized Phase II Evaluation of Carboplatin/Paclitaxel with and without Trastuzumab (Herceptin) in HER2/neu+ Patients with Advanced/Recurrent Uterine Serous Papillary Carcinoma
Phase: Phase II
Sponsor: External Investigator-Sponsored (External Med Ctr)
Principal Investigator: Laura Havrilesky
Contact: GYN Oncology Clinical Trials
Phone: 919.684.3780
Reference Number: 00032751
View this trial at ClinicalTrials.gov

A Phase II Evaluation of BIBF 1120 in the Treatment of Bevacizumab-Resistant persistent or Recurrent Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Carcinoma
Phase: Phase II
Sponsor: PI initiated
Principal Investigator: Angeles Secord
Contact: GYN Oncology Clinical Trials
Phone: 919.684.3780
Reference Number: 00033060
View this trial at ClinicalTrials.gov

A Randomized Open Label Phase II Study of Weekly Gemcitabine Plus Pazopanib Versus Weekly Gemcitabine Alone in the Treatment of Persistent or Relapsed Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Carcinoma
Phase: Phase II
Sponsor: External Investigator-Sponsored (External Med Ctr)
Principal Investigator: Angeles Secord
Contact: Gynecology Oncology Clinical Research Office
Phone: 919.684.3780
Reference Number: 00039020
View this trial at ClinicalTrials.gov

GOG 0225: Can Diet and Physical Activity Modulate Ovarian, Fallopian Tube, and Primary Peritoneal Cancer Progression-Free Survival
Phase: N/A
Sponsor: Cooperative Group Initiated
Principal Investigator: Laura Havrilesky
Contact: Jessie Ehrisman
Phone: 919.684.9065
Reference Number: 00039076
View this trial at ClinicalTrials.gov

GOG 0286B: A Randomized Phase II/III Study of Paclitaxel/Carboplatin/Metformin (NSC#91485) Versus Paclitaxel/Carboplatin/Placebo as Initial Therapy for Measurable Stage III or IVA, Stage IVB, or Recurrent Endometrial Cancer
Phase: Phase II
Sponsor: Cooperative Group Initiated
Principal Investigator: Angeles Secord
Contact: GYN Oncology Clinical Trials
Phone: 919.684.3780
Reference Number: 00049306
View this trial at ClinicalTrials.gov

S1316: Prospective Comparative Effectiveness Trial for Malignant Bowel Obstruction
Phase: N/A
Sponsor: Cooperative Group Initiated
Principal Investigator: Angeles Secord
Contact: GYN Oncology Clinical Trials
Phone: 919.684.3780
Reference Number: 00058895
View this trial at ClinicalTrials.gov

A Phase 2, Open-Label, Single-Arm Study to Evaluate the Safety and Efficacy of Niraparib in Patients with Advanced, Relapsed, High-Grade Serous Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Who Have Received Three or Four Chemotherapy Regimens
Phase: Phase II
Sponsor: Commercial / Industry (for-profit group) initiated
Principal Investigator: Angeles Secord
Contact: Gynecology Oncology Clinical Research Office
Phone: 919.684.3780
Reference Number: 00062414
View this trial at ClinicalTrials.gov

A Phase 3 Placebo-controlled Study of Carboplatin/Paclitaxel With or Without Concurrent and Continuation Maintenance Veliparib (PARP Inhibitor) in Subjects with Previously Untreated Stages III or IV High-Grade Serous Epithelial Ovarian Fallopian Tube, or Primary Peritoneal Cancer
Phase: Phase III
Sponsor: Commercial / Industry (for-profit group) initiated
Principal Investigator: Angeles Secord
Contact: GYNECOLOGY ONCOLOGY CLINICAL TRIALS OFFICE
Phone: 919.684.3780
Reference Number: 00063539
View this trial at ClinicalTrials.gov

NRG-GY005: A Randomized Phase II/III Study of the Combination of Cediranib and Olaparib Compared to Cediranib or Olaparib Alone, or Standard of Care Chemotherapy in Women with Recurrent Platinum-Resistant or -Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (COCOS)
Phase: Phase III
Sponsor: Cooperative Group Initiated
Principal Investigator: Angeles Secord
Contact: GYNECOLOGY ONCOLOGY CLINICAL TRIALS OFFICE
Phone: 919.684.3780
Reference Number: 00070645
View this trial at ClinicalTrials.gov

NRG-GY004: A Phase III Study Comparing Single-Agent Olaparib or the Combination of Cediranib and Olaparib to Standard Platinum-Based Chemotherapy in Women with Recurrent Platinum-Sensitive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Phase: Phase III
Sponsor: Cooperative Group Initiated
Principal Investigator: Angeles Secord
Contact: GYNECOLOGY ONCOLOGY CLINICAL TRIALS OFFICE
Phone: 919.684.3780
Reference Number: 00070659
View this trial at ClinicalTrials.gov