You are here

Researchers and Physicians

Ovarian Cancer Survivors and Families Help Advance Research

It’s been called the silent killer because it spreads fairly quietly, before causing painful symptoms. By the time many women are diagnosed with ovarian cancer, its already advanced through the abdominal cavity. This is what happened to Gail Parkins, who, at the age of 54, was eventually diagnosed...

Blood Biomarkers ID'd in Drug-Resistant Cancer Tumor Cells

While searching for a non-invasive way to detect prostate cancer cells circulating in blood, Duke Cancer Institute researchers have identified some blood markers associated with tumor resistance to two common hormone therapies. In a study published online this month in the journal Clinical Cancer...

Nationwide Ovarian Cancer Clinical Trial Shows Promise

When IBM IT architect Laura Elzie, 60, was first diagnosed with ovarian cancer three years ago by her long-time primary care physician she was momentarily stunned when she heard, “Some of us never know how we are going to leave this world, but at least you know.” For months she’d been told her pain...

Innovative Research the Focus of DCI Scientific Retreat

Duke Cancer Institute hosted the Fourth Annual DCI Scientific Retreat on Friday, Oct. 28, at Bay 7 in the American Tobacco District in Durham. The event featured the second-annual *O. Michael Colvin Memorial Lecture, which was presented by Levi A. Garraway, MD, PhD, of Harvard Medical School and...

Trial Launches for Veterans with Liver Cancer

Primary liver cancer, also known as hepatocellular carcinoma (HCC), is the world’s third most common cause of cancer death. In the United States, the incidence of HCC is increasing. While surgery is the optimal treatment, less than a third of HCC patients are medically fit for surgery or liver...

Mutation Could Be Vulnerable to Drugs

Breast cancer cells that carry a certain gene mutation can be induced to die using a combination of an existing targeted therapy along with an investigational molecule tested by Duke Cancer Institute researchers. When used together in preclinical experiments, the drugs shut down two of the key...

DCI Cancer Clinicians Tackle Financial Toxicity

Financial toxicity. Google it and you’ll find it’s the new catchphrase to describe the escalating costs of cancer care. The leading killer of patients under 85, the national expenditure on cancer is in the $200 billion range and overall patient spending on cancer treatment can easily reach tens of...

Tumor-Seeking Salmonella Treats Brain Tumors

Biomedical engineers at Duke University have recruited an unlikely ally in the fight against the deadliest form of brain cancer — a strain of salmonella that usually causes food poisoning. Clinicians sorely need new treatment approaches for glioblastoma, the most aggressive form of brain cancer...

Prostate Cancer Cells Grow with Malfunction of Cholesterol Control

Advanced prostate cancer and high blood cholesterol have long been known to be connected, but it has been a chicken-or-egg problem. Now a team led by researchers at the Duke Cancer Institute have identified a cellular process that cancer cells hijack to hoard cholesterol and fuel their growth...

Pages