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Clinical Trials

Pediatric Clinical Trials - Pediatric Bone Marrow Transplant

If you would like to inquire about all open trials, please contact 919-684-3401.

Items 1 - 14 of 14

Recombinant Human Growth Hormone (rh-GH) for Accelerating Immune Reconstitution in Pediatric and Adult Patients Undergoing Allogeneic Stem Cell Transplantation
Principal Investigator: Mitchell Horwitz
Phase: Phase I
Phone: 919-668-6536

A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) for transplantation in pediatric and adult patients with hematologic malignancies and other indications
Principal Investigator: Joanne Kurtzberg
Phase: N/A
Phone: 919-668-6536

A SCREENING PROTOCOL TO IDENTIFY PATIENTS WITH ADV VIREMIA POST ALLOGENEIC HSCT A Companion Protocol to the Clinical Study A RANDOMIZED, PLACEBO-CONTROLLED, MULTI-SITE PHASE 2 STUDY EVALUATING THE SAFETY AND EFFICACY OF PREEMPTIVE TREATMENT WITH CMX001 FOR THE PREVENTION OF ADENOVIRUS DISEASE FOLLOWING HEMATOPOIETIC STEM CELL TRANSPLANTATION (THE ADV HALT TRIAL)
Principal Investigator: Joanne Kurtzberg
Phase: Phase II
Phone: 919-668-6536

Fludarabine-Based Conditioning for Allergenic Marrow Transplantation From HLA-Compatible Unrelated Donors in Severe Aplastic Anemia
Principal Investigator: Joanne Kurtzberg
Phase: Phase II
Phone: 919-668-6536

BMT CTM Protocol 1101 - A Multi-Center, Phase III, Randomized Trial of Reduced Intensity (RIC) Conditioning and Transplantation of Double Unrelated Umbilical Cord Blood (dUCB) versus HLA-Haploidentical Related Bone Marrow (Haplo) for Patients with Hematologic Malignancies
Principal Investigator: Joanne Kurtzberg
Phase: Phase III
Phone: 919-668-1100

Pilot Study of Sequential Myeloablative Stem Cell Transplantation and Reduced Intensity Allogeneic Stem Cell Transplantation Followed by Adoptive Cellular Immunotherapy in Patients with Recurrent/Refractory Non-Hodgkin's Lymphoma and Hodgkin's Disease
Principal Investigator: Joanne Kurtzberg
Phase: Pilot / Feasibility
Phone: 919-668-6536

DEFIBROTIDE FOR PATIENTS WITH HEPATIC VENO-OCCLUSIVE DISEASE (VOD): A TREATMENT IND STUDY (UNDER CFR 312.34)
Principal Investigator: Paul Martin
Phase: N/A
Phone: 919-668-6536

The Role of Minimal Residual Disease Testing before and after Hematopoietic Cell Transplantation for Pediatric Acute Myeloid Leukemia
Principal Investigator: Paul Martin
Phase: N/A
Phone: 919-668-6536

Phase II Evaluation of the Safety and Efficacy of TXA127 (Angiotensin 1-7) to Enhance Engraftment in Pediatric Subjects Undergoing Single or Double Umbilical Cord Blood Transplantation
Principal Investigator: Kristin Page
Phase: Phase II
Phone: 919-668-6536

BMT CTN Protocol 0801 A Phase II/III Randomized, Multi-center Trial Comparing Sirolimus Plus Prednisone and Sirolimus/Calcineurin Inhibitor Plus Prednisone for The Treatment of Chronic Graft-versus-Host-Disease
Principal Investigator: Suhag Parikh
Phase: Phase II
Phone: 919-668-6536

Unrelated Donor Hematopoietic Cell Transplantation for Children with Severe Sickle Cell Disease Using a Reduced Intensity Conditioning Regimen
Principal Investigator: Suhag Parikh
Phase: Phase II
Phone: 919-668-6536

A PILOT STUDY OF REDUCED INTENSITY CONDITIONING IN PEDIATRIC PATIENTS < 21 YEARS OF AGE WITH NON-MALIGNANT DISORDERS UNDERGOING UMBILICAL CORD BLOOD TRANSPLANTATION
Principal Investigator: Suhag Parikh
Phase: Pilot / Feasibility
Phone: 919-668-6536

A Multicenter Study of Hematopoietic Stem Cell Donor Safety And Quality of Life
Principal Investigator: Vinod Prasad
Phase: N/A
Phone: 919-668-6536

Treatment Protocol to Evaluate Safety and Treatment Outcomes of Prochymal™ (Ex-vivo Cultured Adult Human Mesenchymal Stem Cells) Infusion for the Treatment of Steroid-Refractory Acute GVHD in Pediatric Patients
Principal Investigator: Vinod Prasad
Phase: N/A
Phone: 919-668-6536