Arthur Moseley, PhD
Institute for Genome Sciences & Policy
School of Medicine
B02 Levine Sciences Research Center
450 Research Drive
Durham, NC 27710
Laboratory phone: 919-668-7633
The DCI Proteomics Shared Resource was designed to provide qualitative and quantitative proteomic support using nanoscale ultraperformance liquid chromatographs (single or multidimensional) coupled to high-resolution accurate-mass tandem mass spectrometers (LC/LC/MS/MS). Located in the Levine Science Research Center in the heart of Duke's biomedical research campus, the Facility is convenient to members of the Duke Cancer Institute (DCI). The Facility's lab space was custom designed as a proteomics facility with adjacent office space for staff and for consultations with users.
Since becoming fully operational in 2008, the Facility has performed more than 900 projects for over 150 PIs. While the Facility is available for use by the entire Duke research community, its CCSG support means that DCI members have priority access and are the first invited to be involved in early-access technology development projects.
Integral to the Proteomics Facility's ability to provide affordable emerging technologies to the DCI are close working relationships between the Proteomics Facility and instrument/software/reagent companies. One example of such a collaboration is with the manufacturer of the majority of our LC and MS tools Waters Corporation, for which the Proteomics Facility is a formal Center of Innovation. This association allows access to beta technologies (such as the microfluidics LC platform), software platforms (Progenesis software), and substantial discounts on instrument acquisitions (most recently for the acquisition of the TQ-S triple quadrupole mass spectrometer).
The Proteomics Facility operational model is to serve the DCI as a collaborative, customer-focused "Force Amplifier" for biomedical research; offering interactive, efficient, and cost-effective state-of-the-art proteomics technologies.
For more information, please visit: http://www.genome.duke.edu/cores/proteomics/
For more information on equipment, please visit: http://www.genome.duke.edu/cores/proteomics/instrumentation/index.php
Prior to submitting a sample, please arrange for a consultation with Arthur Moseley, Will Thompson, or Erik Soderblom. Please note: Samples will not be accepted without prior consultation. Priorization will be given to time-sensative projects, including preliminary data needed for timely grant submissions and additional experiments needed for resubmission of manuscripts.
Sample submission and data return from the Duke Proteomics Core Facility takes advantage of the IGSP data repository to return customer data in digital format. This submission and data return protocol uses the IGSPnet, which can be accessed by both Duke and non-Duke collaborators. Three steps are required to submit a sample to our facility:
**Note**: The first time you wish to submit a sample, we will have to grant you access to the submissions page. Email a facility member with your netID and we will enable your account.
While the Facility is available for use by all Duke researchers, its support from the CCSG translates into priority access for DCI members.
For more information on sample submission, please visit: http://www.genome.duke.edu/cores/proteomics/submission/
For current pricing information, please visit: http://www.genome.duke.edu/cores/proteomics/pricing/