Repare RP-3500-01 (Advanced Solid Tumors)
What is the Purpose of this Study?
-Go through a screening period to see if you qualify for the study
-Take the study drug (RP-3500) by mouth 1 or 2 times a day according to the assigned schedule
-Provide old tumor tissue
-Have physical exams, blood and urine tests
-Have imaging scans (CT and/or MRI)
Some people will also:
-Take talazoparib by mouth once daily
-Have tumor samples taken
Who Can Participate in this Study?
Adults with advanced cancer resistant to standard treatment with documented changes in certain genes.
What is Involved?
We are doing this study to find out the safest and most effective dose of the study drug (RP-3500) is when given alone or in combination with talazoparib.