Bellicum BPX-601 (Prostate Cancer)
What is the Purpose of this Study?
- Undergo leukapheresis to collect your white blood cells or T-cells to make the study drug
- Receive lympho-depleting chemotherapy
- Take the study drug along with rimiducid
- Provide tumor tissue
- Have physical exams, blood draws, and give urine samples
- Have imaging scans (CT and/or MRI)
- Have heart tests (ECG)
- Have bone scans
Who Can Participate in this Study?
Adults ages 18+ who:
- Are diagnosed with prostate cancer that has spread (metastatic)
- Have received at least one round of previous treatment
- Have never received treatment with CAR T cell or other modified T cell therapies
For more information about who can join this study, please contact the study team at CCI-TrialReferrals@duke.edu or 919-681-6468.
What is Involved?
We are doing this study to find out if an experimental drug called BPX-601 (the study drug) is a safe and effective treatment for your cancer when it's given with another experimental drug called rimiducid. The study drug is custom-made for each participant from their own white blood cells or T-cells. We collect these cells using a procedure called leukapheresis.