What is the Purpose of this Study?
We are doing this study to compare the effects (good and/or bad) of cisplatin with the combination of chemotherapy in treating children and young adults with hepatoblastoma or liver cancer after surgery.
Children and young adults with Hepatoblastoma
Who Can Participate in the Study?
Adults and children who:
- Are up to age 30
- Have a newly diagnosed primary pediatric hepatic malignancy
What is Involved?
If you choose to join this study, you will:
- Get treatments based on the group you are assigned
-- Group A: patients with very low risk disease
-- Group B: patients with low risk disease
-- Group C: patients with intermediate risk disease
-- Group D: patients with high risk disease
Depending on your assigned group, you may:
-- Get chemotherapy drugs such as cisplatin, doxorubicin, fluorouracil, vincristine sulfate, carboplatin, etoposide, irinotecan, sorafenib, gemcitabine and/or oxaliplatin.
--- Be randomized (like flipping a coin) to different types or doses of chemotherapy
-- Have surgery to remove your tumor