AHEP1531: Hepatoblastoma in Children & Young Adults

We are doing this study to compare the effects (good and/or bad) of cisplatin with the combination of chemotherapy in treating children and young adults with hepatoblastoma or liver cancer after surgery.

Children and young adults with Hepatoblastoma

Adults and children who:
- Are up to age 30
- Have a newly diagnosed primary pediatric hepatic malignancy

If you choose to join this study, you will:
- Get treatments based on the group you are assigned

-- Group A: patients with very low risk disease
-- Group B: patients with low risk disease
-- Group C: patients with intermediate risk disease
-- Group D: patients with high risk disease

Depending on your assigned group, you may:
-- Get chemotherapy drugs such as cisplatin, doxorubicin, fluorouracil, vincristine sulfate, carboplatin, etoposide, irinotecan, sorafenib, gemcitabine and/or oxaliplatin.
--- Be randomized (like flipping a coin) to different types or doses of chemotherapy
-- Have surgery to remove your tumor