Astellas 2074-CL-0101 (GI Cancers)

What is the Purpose of this Study?

We are doing this study to find out if an experimental drug called ASP2074 (the study drug) is a safe and effective treatment for different types of GI cancers.

What is the Condition Being Studied?

Gastrointestinal (GI) Cancers

Who Can Participate in the Study?

Adults ages 18+ who are diagnosed with the following GI cancers that have spread:
- Colorectal cancer
- Pancreatic cancer
- Gastric cancer
- Esophageal cancer
- GEJ adenocarcinoma

For more information about who can join this study, please contact the study team at 919-681-6468.

Age Group
Adults

What is Involved?

If you choose to join this study, you will:
- Receive the study drug as an infusion (IV)
- Provide tumor tissue
- Have physical exams, blood draws, and give urine samples
- Have imaging scans (CT and/or MRI)
- Have heart tests (ECG)

Study Details

Full Title
A Phase 1/1b Study of ASP2074 in Participants with Metastatic or Locally Advanced Solid Tumors
Principal Investigator
Assistant Professor of Medicine
Protocol Number
IRB: PRO00112419
NCT: NCT05646797
Phase
Phase I
ClinicalTrials.gov
Enrollment Status
OPEN TO ACCRUAL