Jason Locasale
Associate Professor of Pharmacology and Cancer Biology
Overview
Our research interests are in three interconnected areas: 1) Quantitative and computational biology of metabolism. 2) The role of diet and pharmacological therapeutics in shaping metabolic pathways in health and cancer. 3) The interaction of metabolism and epigenetics. Each of these synergistic areas utilizes the metabolomics technologies we develop along with our expertise in computational and molecular biology.
Positions
Associate Professor of Pharmacology and Cancer Biology in the School of Medicine
2018 School of Medicine
Member of Duke Molecular Physiology Institute in the School of Medicine
2013 School of Medicine
Member of the Duke Cancer Institute in the School of Medicine
2015 School of Medicine
Education
B.A. 2003
2003 Rutgers University New Brunswick
Ph.D. 2008
2008 Massachusetts Institute of Technology
Publications, Grants & Awards
- Academics Articles (270)
- Conference Pages (17)
- Book Sections (3)
Cancer Discov
Trends Cancer
The Journal of Biological Chemistry
Cell Reports
Nature Communications
Cancer Discov
Nature
Cell Stress
Curr Opin Chem Biol
Ca: a Cancer Journal for Clinicians
Proc Natl Acad Sci U S A
Cell Reports
J Immunol
Proc Natl Acad Sci U S A
Embo Mol Med
Nature Communications
Nat Rev Genet
Nature Communications
Cancer Discov
Nature Metabolism
Nature Communications
Curr Opin Biotechnol
Nature Communications
Nat Immunol
Nature Metabolism
Cell Metab
Trends in Biochemical Sciences
Nat Cell Biol
The Journal of Biological Chemistry
Angew Chem Int Ed Engl
Nature Communications
Nat Immunol
Trends Cell Biol
Nature Communications
Mol Cancer Res
Nature Communications
Cell Reports
Science Immunology
Science Advances
The Journal of Biological Chemistry
Nature Communications
Nature Communications
Comparative Exercise Physiology
The Journal of Biological Chemistry
Nature Communications
Nature Communications
Current Opinion in Systems Biology
Cell Reports
Cancer & Metabolism
Cell Reports
The Journal of Biological Chemistry
The Embo Journal
Mol Aspects Med
Trends in Biochemical Sciences
Trends in Cancer
Molecular Systems Biology
Exp Gerontol
Cell Chem Biol
Cancer & Metabolism
Nature Communications
Nat Immunol
Cell Metab
Nat Cell Biol
Biophysical Journal
Nat Chem Biol
Proc Natl Acad Sci U S A
Cell Reports
Trends in Biochemical Sciences
Trends in Biochemical Sciences
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
Ann N Y Acad Sci
Comput Biol Chem
Semin Cancer Biol
Semin Cancer Biol
Cell Metab
Molecular & Cellular Proteomics : Mcp
Molecular & Cellular Oncology
Biochimica Et Biophysica Acta
Embo Reports
Curr Opin Biotechnol
Molecular & Cellular Proteomics : Mcp
Cancer Lett
Cancer & Metabolism
Crit Rev Food Sci Nutr
Biochem Pharmacol
Plos Computational Biology
Cell Death & Disease
Cell Death & Disease
Journal of Visualized Experiments : Jove
The Journal of Biological Chemistry
Proceedings of the National Academy of Sciences of the United States of America
Proc Natl Acad Sci U S A
Mol Cancer Res
Cancer & Metabolism
Cell Death & Disease
Annu Int Conf IEEE Eng Med Biol Soc
Nat Biotechnol
Nat Struct Mol Biol
Wiley Interdiscip Rev Syst Biol Med
Trends Endocrinol Metab
Molecular Systems Biology
Molecular & Cellular Proteomics : Mcp
Biomedical Research (India)
Journal of Clinical Oncology
Bmc Proceedings
Frontiers in Oncology
Clinical Cancer Research
Pigment Cell Melanoma Res
Neuro Oncology
Neuro Oncology
Mol Cell
Cancer Research
Sci Signal
Cold Spring Harb Symp Quant Biol
Journal of Biomolecular Techniques : Jbt
Bmc Biology
Proc Natl Acad Sci U S A
Nat Biotechnol
Plos One
Bmc Systems Biology
Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
Plos Computational Biology
Faseb Journal
The Journal of Chemical Physics
Abstracts of Papers of the American Chemical Society
Proceedings of the National Academy of Sciences of the United States of America
Journal of Neurosurgery
Molecular and Cellular Biology / Genetics
Faseb Journal
Circulation Research
Cancer Research
Cancer Research
Cancer Research
Cancer Research
Molecular Biology of the Cell
European Journal of Cancer
Abstracts of Papers of the American Chemical Society
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
Faseb Journal
Faseb Journal
Abstracts of Papers of the American Chemical Society
Abeloff’s Clinical Oncology
Systems Biology of Cancer
Insulin-like Growth Factors and Cancer: From Basic Biology to Therapeutics