Erika Crosby

Overview:

Dr. Crosby received her PhD in Immunology from the University of Pennsylvania where she used models of chronic infection to understand how the immune system causes damage to healthy tissue. She arrived at Duke for a postdoctoral fellowship where she applied this knowledge to test new therapies that bypass this immune system regulation to treat breast cancer. Dr. Crosby remained at Duke to start her own research program in 2021.

Positions:

Assistant Professor in Surgery

Surgery, Surgical Sciences
School of Medicine

Member of the Duke Cancer Institute

Duke Cancer Institute
School of Medicine

Education:

B.S. 2009

Bucknell University

Ph.D. 2014

University of Pennsylvania

Grants:

Defining a CXCR3-associated gene signature as a predictive biomarker and alternate target of immunotherapy across molecular subtypes of breast cancer

Administered By
Surgery, Surgical Sciences
Awarded By
National Institutes of Health
Role
Principal Investigator
Start Date
End Date

Publications:

Key takeaways for knowledge expansion of early-career scientists conducting Transdisciplinary Research in Energetics and Cancer (TREC): a report from the TREC Training Workshop 2022.

The overall goal of the annual Transdisciplinary Research in Energetics and Cancer (TREC) Training Workshop is to provide transdisciplinary training for scientists in energetics and cancer and clinical care. The 2022 Workshop included 27 early-to-mid career investigators (trainees) pursuing diverse TREC research areas in basic, clinical, and population sciences. The 2022 trainees participated in a gallery walk, an interactive qualitative program evaluation method, to summarize key takeaways related to program objectives. Writing groups were formed and collaborated on this summary of the 5 key takeaways from the TREC Workshop. The 2022 TREC Workshop provided a targeted and unique networking opportunity that facilitated meaningful collaborative work addressing research and clinical needs in energetics and cancer. This report summarizes the 2022 TREC Workshop's key takeaways and future directions for innovative transdisciplinary energetics and cancer research.
Authors
Kung, C-P; Skiba, MB; Crosby, EJ; Gorzelitz, J; Kennedy, MA; Kerr, BA; Li, YR; Nash, S; Potiaumpai, M; Kleckner, AS; James, DL; Coleman, MF; Fairman, CM; Galván, GC; Garcia, DO; Gordon, MJ; His, M; Hornbuckle, LM; Kim, S-Y; Kim, T-H; Kumar, A; Mahé, M; McDonnell, KK; Moore, J; Oh, S; Sun, X; Irwin, ML
MLA Citation
Kung, Che-Pei, et al. “Key takeaways for knowledge expansion of early-career scientists conducting Transdisciplinary Research in Energetics and Cancer (TREC): a report from the TREC Training Workshop 2022.” J Natl Cancer Inst Monogr, vol. 2023, no. 61, May 2023, pp. 149–57. Pubmed, doi:10.1093/jncimonographs/lgad005.
URI
https://scholars.duke.edu/individual/pub1575683
PMID
37139978
Source
pubmed
Published In
J Natl Cancer Inst Monogr
Volume
2023
Published Date
Start Page
149
End Page
157
DOI
10.1093/jncimonographs/lgad005

Supplementary Figure 5 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

<jats:p>&lt;p&gt;TruRegistry of HER2BOW tissues&lt;/p&gt;</jats:p>
Authors
Ginzel, JD; Acharya, CR; Lubkov, V; Mori, H; Boone, PG; Rochelle, LK; Roberts, WL; Everitt, JI; Hartman, ZC; Crosby, EJ; Barak, LS; Caron, MG; Chen, JQ; Hubbard, NE; Cardiff, RD; Borowsky, AD; Lyerly, HK; Snyder, JC
MLA Citation
URI
https://scholars.duke.edu/individual/pub1571955
Source
crossref
Published Date
DOI
10.1158/1541-7786.22526390.v1

Movie 4 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

<jats:p>&lt;p&gt;p95HER2 microinvasive carcinoma. p95HER2 shown in magenta. Krt14 antibody staining shown in green.&lt;/p&gt;</jats:p>
Authors
Ginzel, JD; Acharya, CR; Lubkov, V; Mori, H; Boone, PG; Rochelle, LK; Roberts, WL; Everitt, JI; Hartman, ZC; Crosby, EJ; Barak, LS; Caron, MG; Chen, JQ; Hubbard, NE; Cardiff, RD; Borowsky, AD; Lyerly, HK; Snyder, JC
MLA Citation
URI
https://scholars.duke.edu/individual/pub1571971
Source
crossref
Published Date
DOI
10.1158/1541-7786.22526411

Table S2 from Vaccine-Induced Memory CD8&lt;sup&gt;+&lt;/sup&gt; T Cells Provide Clinical Benefit in HER2 Expressing Breast Cancer: A Mouse to Human Translational Study

<jats:p>&lt;p&gt;Concurrent HER2 therapies for each patient for whom CYTOF analysis was done&lt;/p&gt;</jats:p>
Authors
Crosby, EJ; Gwin, W; Blackwell, K; Marcom, PK; Chang, S; Maecker, HT; Broadwater, G; Hyslop, T; Kim, S; Rogatko, A; Lubkov, V; Snyder, JC; Osada, T; Hobeika, AC; Morse, MA; Lyerly, HK; Hartman, ZC
MLA Citation
URI
https://scholars.duke.edu/individual/pub1571740
Source
crossref
Published Date
DOI
10.1158/1078-0432.22472847

Supplementary Figure 1 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

<jats:p>&lt;p&gt;HER2BOW transgene design&lt;/p&gt;</jats:p>
Authors
Ginzel, JD; Acharya, CR; Lubkov, V; Mori, H; Boone, PG; Rochelle, LK; Roberts, WL; Everitt, JI; Hartman, ZC; Crosby, EJ; Barak, LS; Caron, MG; Chen, JQ; Hubbard, NE; Cardiff, RD; Borowsky, AD; Lyerly, HK; Snyder, JC
MLA Citation
URI
https://scholars.duke.edu/individual/pub1571956
Source
crossref
Published Date
DOI
10.1158/1541-7786.22526402
Assistant Professor in Surgery

Contact:

Profile

https://scholars.duke.edu/person/erika.crosby

Email

erika.crosby@duke.edu
203 Research Drive, Msrb1 Box 2606, Durham, NC 27710
Msrb1 Room 288, Durham, NC 27710