Our multidisciplinary disease group includes endocrine surgeons, endocrinologists, head and neck (ENT) surgeons, medical oncologists, radiation oncologists, a dedicated endocrine diagnostic radiology and pathology group, specialized advanced practice providers, nurses, social workers, nutritionists, genetic counselors and others.
We offer personalized therapies based on biopsies or small tissue samples as well as molecular testing, which means that treatments are tailored to the specific type of cancer.
Our surgeons have performed thousands of neck and abdominal endocrine-specific surgical procedures, ranging from minimally invasive to complex. Novel surgical techniques are employed, including parathyroid and thyroid surgery under local anesthesia and minimally invasive adrenal surgery through the back. Our endocrinologists are sub-specialized, focusing their entire clinical practice in treating all forms of endocrine neoplasia disease and working alongside surgeons to ensure optimal treatment pre-operatively, during surgery, and post-operatively.
We strive for lower complication rates, shorter hospital stays, lower overall costs, less likelihood of cancer recurrence and fewer repeat operations as compared to national published data.
Challenging cases are discussed in a multidisciplinary fashion at a weekly tumor board attended by experts from surgery, endocrinology, pathology, radiology and oncology.
We also offer patient support services to assist patients in maintaining quality of life throughout treatment and recovery. Both adult and pediatric patients have convenient and rapid access to appointments in both Raleigh and Durham Duke Cancer Center locations.
As a National Cancer Institute-designated Comprehensive Cancer Center, our thyroid cancer group is recognized for exploring new treatment opportunities. We work with the American Thyroid Association, American Association of Endocrine Surgeons and National Comprehensive Center Network to help set the national standards for best practice treatment guidelines. We were also one of the first institutions to work with the Collaborative Endocrine Surgery Quality Improvement Program to improve quality in endocrine surgery.
Our disease group specializes in:
Diseases of the Thyroid
- Thyroid cancer
- Thyroid nodule/mass
- Thyroid goiter
- Toxic multinodular goiter
- Toxic adenoma
- Graves’ disease/Hyperthyroidism
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- Hyperparathyroidism (primary, secondary, tertiary, recurrent)
- Parathyroid cancer
- Parathyroid adenoma
Adrenal Gland Disorders
- Adrenal nodule/mass (functional or not)
- Adrenal cancer
- Cushing’s Syndrome
- Conn’s Syndrome
- Pheochromocytoma or hyperaldosteronism
- Primary aldosteronism
Our research encompasses the different diseases of the thyroid, parathyroid, pancreas, and adrenal glands.
- Health Services Research
- Patient-Reported Outcomes
- Translational Research: The endocrine neoplasia group has an encompassing interest in cross-disciplinary translational research, including parathyroid diseases (Koh Laboratory), and thyroid cancer (Counter Laboratory; Stapleton Laboratory)
- Cancer Genetics: The endocrine neoplasia group has been working using genomic data of thyroid cancer, to develop a genetic signature that predicts progression. (Cheng Laboratory)
- Clinical Trials
Research Programs and Centers:
We are among the first to enroll patients in clinical studies investigating small-molecule therapies for locally advanced and metastatic thyroid cancer. Our expanding portfolio of clinical trials and growing tissue bank opens our patients’ access to experimental uses of approved drugs and newer therapies, including selumetinib, vandetanib (Caprelsa), cabozantinib (Cometriq) and sorafenib (Nexavar).