David R. Sherwood
Professor of BiologyOverview
The Sherwood lab is interested in understanding mechanisms that drive dynamic cellular behaviors underlying normal development and human disease. We study 1) How cells invade into tissues, 2) How stem cells interact with their niches, and 3) How cells control and interact with extracellular matrix. Our lab primarily examines C. elegans development, in which simple cellular complexity, amenability to genetics/genomics/transgenics/molecular perturbations, and evolutionary comparisons facilitates powerful insights. One particular emphasis of our work is live-cell imaging, where we watch cellular behaviors and cell-extracellular matrix interactions unfold in real-time to understand their regulation and function. Cell invasion, stem cell regulation, and cell-matrix interactions are fundamental to development, regeneration, cancer, and aging. Our work aims to advance our understanding of these fascinating processes and positively influence human health.
Positions
Professor of Biology in the Trinity College of Arts & Sciences
2017 Trinity College of Arts & Sciences
Associate Chair of the Department of Biology in the Trinity College of Arts & Sciences
2018 Trinity College of Arts & Sciences
Professor in Molecular Genetics and Microbiology in the School of Medicine
2024 School of Medicine
Associate Professor in Cell Biology in the School of Medicine
2016 School of Medicine
Co-Director of the Duke Regeneration Center in the School of Medicine
2021 School of Medicine
Member of the Duke Cancer Institute in the School of Medicine
2019 School of Medicine
Education
B.A. 1990
1990 Wesleyan University
Ph.D. 1997
1997 Duke University
Co-Director Embryology Course, MARINE BIOLOGICAL LABORATORY
2022 Other
Publications, Grants & Awards
Offices & Contact
Box 90338
Durham, NC
27708
Duke Box 90338
Durham, NC
27708-1000