David Sherwood
Jerry G. and Patricia Crawford Hubbard Professor
Overview
The Sherwood lab is interested in understanding mechanisms that drive dynamic cellular behaviors underlying normal development and human disease. We study 1) How cells invade into tissues, 2) How stem cells interact with their niches, and 3) How cells control and interact with extracellular matrix. Our lab primarily examines C. elegans development, in which simple cellular complexity, amenability to genetics/genomics/transgenics/molecular perturbations, and evolutionary comparisons facilitates powerful insights. One particular emphasis of our work is live-cell imaging, where we watch cellular behaviors and cell-extracellular matrix interactions unfold in real-time to understand their regulation and function. Cell invasion, stem cell regulation, and cell-matrix interactions are fundamental to development, regeneration, cancer, and aging. Our work aims to advance our understanding of these fascinating processes and positively influence human health.
Positions
Jerry G. and Patricia Crawford Hubbard Professor in the Trinity College of Arts & Sciences
2019 Trinity College of Arts & Sciences
Professor of Biology in the Trinity College of Arts & Sciences
2017 Trinity College of Arts & Sciences
Associate Chair of the Department of Biology in the Trinity College of Arts & Sciences
2023 Trinity College of Arts & Sciences
Associate Professor in Cell Biology in the School of Medicine
2016 School of Medicine
Member of the Duke Cancer Institute in the School of Medicine
2019 School of Medicine
Co-Director of the Duke Regeneration Center in the School of Medicine
2021 School of Medicine
Education
B.A. 1990
1990 Wesleyan University
Ph.D. 1997
1997 Duke University
Publications, Grants & Awards
- Grants (30)
- Awards (4)
- Academics Articles (90)
- Conference Pages (33)
- Book Sections (1)
National Institutes of Health
National Institutes of Health
National Institutes of Health
Jane Coffin Childs Memorial Fund for Medical Research
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
University of Manchester
National Institutes of Health
National Institutes of Health
American Cancer Society, Inc.
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Cancer Institute
National Institutes of Health
Damon Runyon Cancer Research Foundation
National Institutes of Health
National Institutes of Health
National Institutes of Health
American Cancer Society
Institut Curie, Paris
March of Dimes
Pew Charitable Trusts, The
Seminars in Cell & Developmental Biology
F1000research
Development (Cambridge, England)
The Journal of Cell Biology
Science Advances
Developmental Cell
Frontiers in Cell and Developmental Biology
Current Opinion in Cell Biology
Trends in Cell Biology
Developmental Cell
Developmental Dynamics : an Official Publication of the American Association of Anatomists
European Journal of Cell Biology
Micropublication Biology
The Journal of Cell Biology
Developmental Cell
Current Biology : Cb
Developmental Cell
Matrix Biology : Journal of the International Society for Matrix Biology
Journal of Microbiology & Biology Education
American Journal of Physiology. Cell Physiology
Proceedings of the National Academy of Sciences of the United States of America
Scientific Reports
Developmental Cell
Nature Protocols
Developmental Biology
Current Biology : Cb
Current Biology : Cb
European Journal of Cell Biology
Nanotoxicology
Developmental Cell
Plos Genetics
Developmental Cell
The Journal of Cell Biology
Journal of Cell Science
Current Topics in Membranes
Development (Cambridge, England)
Developmental Cell
Biochemical and Biophysical Research Communications
The Journal of Cell Biology
Nature Communications
Cell Adhesion & Migration
Developmental Cell
Development (Cambridge, England)
The Journal of Cell Biology
The Journal of Cell Biology
The Journal of Cell Biology
Wiley Interdisciplinary Reviews. Developmental Biology
Nature Cell Biology
Current Opinion in Cell Biology
Developmental Biology
Methods in Cell Biology
Science Signaling
Developmental Dynamics : an Official Publication of the American Association of Anatomists
Science Signaling
Gene Expression Patterns : Gep
Developmental Cell
Developmental Biology
The Journal of Cell Biology
Nature Cell Biology
Trends in Cell Biology
Developmental Cell
Mechanisms of Development
Gene Expression Patterns : Gep
Developmental Biology
Development (Cambridge, England)
Development (Cambridge, England)
Drug Metabolism and Pharmacokinetics
Molecular Biology of the Cell
Drug Metabolism and Pharmacokinetics
Molecular Biology of the Cell
Molecular Biology of the Cell
Molecular Biology of the Cell
Molecular Biology of the Cell
Molecular Biology of the Cell
Molecular Biology of the Cell
Molecular Biology of the Cell
Integrative and Comparative Biology
Integrative and Comparative Biology
Integrative and Comparative Biology
Integrative and Comparative Biology
Molecular Biology of the Cell
Molecular Biology of the Cell
Molecular Biology of the Cell
Molecular Biology of the Cell
Molecular Biology of the Cell
Integrative and Comparative Biology
Molecular Biology of the Cell
Molecular Biology of the Cell
Molecular Biology of the Cell
Molecular Biology of the Cell
Molecular Biology of the Cell
REGULATORY PROCESSES IN DEVELOPMENT
Developmental Biology
Molecular Biology of the Cell
Developmental Biology
Molecular Biology of the Cell
Developmental Biology
Extracellular Matrix in Tumor Biology
Offices & Contact
Durham, NC
27708 Duke Box 90338
Durham, NC
27708-1000