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Jeffrey Everitt

Professor Emeritus in Pathology

Jeffrey Everitt

Positions

Professor Emeritus in Pathology in the School of Medicine

2023 School of Medicine

Member of the Duke Cancer Institute in the School of Medicine

2017 School of Medicine

Education

D.V.M. 1977

1977 Cornell University

Publications, Grants & Awards

Grants (8)
Academics Articles (252)
Book Sections (16)
Conference Pages (10)

Stable therapy in Pompe disease through genome editing

2021-2026 National Institutes of Health

Oxidative stress mechanisms regulating gamma-globin gene transcription in sickle cell disease

2022-2026 National Institutes of Health

Targeted Thermal Modulation with Smart Radiometric Monitoring for Effective and Long-Lasting Opioid-Free Pelvic Pain Relief

2023-2024 H3Pelvic Therapy Systems, Inc.

Oxidative Stress and Regional Airway Remodeling and Fibrosis in Obese Asthma

2020-2024 National Institutes of Health

Combatting Bladder Cancer by Inducing Epithelial Turnover

2019-2021 National Institutes of Health

Advanced Technologies for Reducing Decompression Obligation and Risk

2018-2020 Creare, Inc.

Molecular Genetics of BBS

2002-2019 National Institutes of Health

Empowering Duke's Precision Pathology Center with Quantitative Image Analysis to Support Discovery, Diagnostic Assay Development, and Immune Cell Monitoring

2018-2019 North Carolina Biotechnology Center

Is statistical re-evaluation of hemolymphoreticular neoplasms from aspartame studies valid?

September 28, 2023 Toxicological Sciences

Spontaneous episodic inflammation in the intestines of mice lacking HNF4A is driven by microbiota and associated with early life microbiota alterations.

August 31, 2023 Mbio

KeyLoop retractor for global gasless laparoscopy: evaluation of safety and feasibility in a porcine model.

August 01, 2023 Surgical Endoscopy

Genome editing using Staphylococcus aureus Cas9 in a canine model of glycogen storage disease Ia.

June 08, 2023 Molecular Therapy Methods & Clinical Development

Rescue of glutaric aciduria type I in mice by liver-directed therapies.

April 19, 2023 Sci Transl Med

Supplementary Figure 6 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Supplementary Figure 5 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Supplementary Figure 1 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Movie 1 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Movie 3 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Supplementary File 1 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Movie 4 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Supplementary Figure 1 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Supplementary Figure 7 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Movie 5 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Supplementary Figure 7 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Supplementary Figure 4 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Supplementary Figure 6 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Movie 2 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Supplementary Figure 2 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Supplementary Figure 4 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Supplementary Figure 2 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Movie 4 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Supplementary File 1 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Supplementary Figure 3 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Supplementary Tables 1-5 for scRNAseq marker genes from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Movie 5 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Movie 1 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Supplementary Figure 5 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Data from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Movie 3 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Supplementary Tables 1-5 for scRNAseq marker genes from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Supplementary Figure 3 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Movie 2 from HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase

April 03, 2023

Supplementary table TS1 from Neoadjuvant Radiation Therapy and Surgery Improves Metastasis-Free Survival over Surgery Alone in a Primary Mouse Model of Soft Tissue Sarcoma

April 03, 2023

Supplementary figure FS4 from Neoadjuvant Radiation Therapy and Surgery Improves Metastasis-Free Survival over Surgery Alone in a Primary Mouse Model of Soft Tissue Sarcoma

April 03, 2023

Supplementary figure FS4 from Neoadjuvant Radiation Therapy and Surgery Improves Metastasis-Free Survival over Surgery Alone in a Primary Mouse Model of Soft Tissue Sarcoma

April 03, 2023

Supplementary figure FS1 from Neoadjuvant Radiation Therapy and Surgery Improves Metastasis-Free Survival over Surgery Alone in a Primary Mouse Model of Soft Tissue Sarcoma

April 03, 2023

Supplementary figure FS2 from Neoadjuvant Radiation Therapy and Surgery Improves Metastasis-Free Survival over Surgery Alone in a Primary Mouse Model of Soft Tissue Sarcoma

April 03, 2023

Supplementary figure FS3 from Neoadjuvant Radiation Therapy and Surgery Improves Metastasis-Free Survival over Surgery Alone in a Primary Mouse Model of Soft Tissue Sarcoma

April 03, 2023

Supplementary figure FS1 from Neoadjuvant Radiation Therapy and Surgery Improves Metastasis-Free Survival over Surgery Alone in a Primary Mouse Model of Soft Tissue Sarcoma

April 03, 2023

Supplementary figure FS2 from Neoadjuvant Radiation Therapy and Surgery Improves Metastasis-Free Survival over Surgery Alone in a Primary Mouse Model of Soft Tissue Sarcoma

April 03, 2023

Supplementary table TS1 from Neoadjuvant Radiation Therapy and Surgery Improves Metastasis-Free Survival over Surgery Alone in a Primary Mouse Model of Soft Tissue Sarcoma

April 03, 2023

Supplementary figure FS3 from Neoadjuvant Radiation Therapy and Surgery Improves Metastasis-Free Survival over Surgery Alone in a Primary Mouse Model of Soft Tissue Sarcoma

April 03, 2023

An injectable PEG-like conjugate forms a subcutaneous depot and enables sustained delivery of a peptide drug.

March 01, 2023 Biomaterials

Maternal exposure to perfluorobutane sulfonate (PFBS) during pregnancy: evidence of adverse maternal and fetoplacental effects in New Zealand White (NZW) rabbits.

February 17, 2023 Toxicological Sciences

Whole-Slide Cytometric Feature Mapping for Distinguishing Tumor Genomic Subtypes in Head and Neck Squamous Cell Carcinoma Whole-Slide Images.

February 01, 2023 The American Journal of Pathology

Neoadjuvant Radiation Therapy and Surgery Improves Metastasis-Free Survival over Surgery Alone in a Primary Mouse Model of Soft Tissue Sarcoma.

January 03, 2023 Mol Cancer Ther

Anti-adhesive bioresorbable elastomer-coated composite hernia mesh that reduce intraperitoneal adhesions.

January 01, 2023 Biomaterials

Pathologists' perspective on the study design, analysis, and interpretation of proliferative lesions in lifetime and prenatal rodent carcinogenicity bioassays of aspartame.

January 01, 2023 Food Chem Toxicol

Mixed-surface polyamidoamine polymer variants retain nucleic acid-scavenger ability with reduced toxicity.

December 22, 2022 Iscience

Veterinary Management of Harderian Gland Tumors in Cancer Rainbow (crainbow) HER2-Positive Mice.

December 01, 2022 Comp Med

A Non-Invasive Deep Photoablation Technique to Inhibit DCIS Progression and Induce Antitumor Immunity.

November 23, 2022 Cancers

Cas13d knockdown of lung protease Ctsl prevents and treats SARS-CoV-2 infection.

October 01, 2022 Nat Chem Biol

Proceedings of the 2022 National Toxicology Program Satellite Symposium.

October 01, 2022 Toxicol Pathol

Evaluating maternal exposure to an environmental per and polyfluoroalkyl substances (PFAS) mixture during pregnancy: Adverse maternal and fetoplacental effects in a New Zealand White (NZW) rabbit model.

September 10, 2022 The Science of the Total Environment

Genetically manipulating endogenous Kras levels and oncogenic mutations in vivo influences tissue patterning of murine tumorigenesis.

September 07, 2022 Elife

Automated Nuclear Segmentation in Head and Neck Squamous Cell Carcinoma Pathology Reveals Relationships between Cytometric Features and ESTIMATE Stromal and Immune Scores.

September 01, 2022 The American Journal of Pathology

Selected Resources for Pathology Evaluation of Nonhuman Primates in Nonclinical Safety Assessment.

July 01, 2022 Toxicol Pathol

Safety evaluation of carbon tetrafluoride as an inert hyperbaric breathing gas in Sprague-Dawley rats.

June 01, 2022 Toxicol Appl Pharmacol

Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity.

February 07, 2022 Dev Cell

Î²-Cyclodextrin-containing polymer treatment of cutaneous lupus and influenza improves outcomes.

February 02, 2022 Molecular Therapy : the Journal of the American Society of Gene Therapy

The Role of Machine Learning in Cardiovascular Pathology.

February 01, 2022 Can J Cardiol

Update on the Features and Measurements of Experimental Acute Lung Injury in Animals: An Official American Thoracic Society Workshop Report.

February 01, 2022 Am J Respir Cell Mol Biol

Exome sequencing of hepatocellular carcinoma in lemurs identifies potential cancer drivers: A pilot study.

January 01, 2022 Evolution, Medicine, and Public Health

Whole-slide cytometric feature mapping for distinguishing tumor genomic subtypes in HNSCC whole slide images

January 01, 2022

Bioethical, Reproducibility, and Translational Challenges of Animal Models.

December 31, 2021 Ilar J

Poly(lactide-co-Îµ-caprolactone) scaffold promotes equivalent tissue integration and supports skin grafts compared to a predicate collagen scaffold.

November 01, 2021 Wound Repair Regen

Radiologic-pathologic analysis of increased ethanol localization and ablative extent achieved by ethyl cellulose.

October 19, 2021 Scientific Reports

HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase.

October 01, 2021 Mol Cancer Res

Optimizingï»¿ ethyl cellulose-ethanol delivery towards enabling ablation of cervical dysplasia.

August 19, 2021 Scientific Reports

ARHGEF26 enhances Salmonella invasion and inflammation in cells and mice.

July 01, 2021 Plos Pathog

Letter to the Editor Regarding "Pathology Informatics Education Committee of the American College of Veterinary Pathologists (ACVP)".

June 01, 2021 Toxicol Pathol

Ex Vivo MR Histology and Cytometric Feature Mapping Connect Three-dimensional in Vivo MR Images to Two-dimensional Histopathologic Images of Murine Sarcomas.

May 01, 2021 Radiol Imaging Cancer

Polymer-assisted intratumoral delivery of ethanol: Preclinical investigation of safety and efficacy in a murine breast cancer model.

January 01, 2021 Plos One

Injectable non-immunogenic PEG-like conjugate that forms a subcutaneous depot and enables sustained delivery of a peptide drug

January 01, 2021

International Harmonization of Nomenclature and Diagnostic Criteria (INHAND): Non-proliferative and Proliferative Lesions of the Non-human Primate (M. fascicularis).

January 01, 2021 Journal of Toxicologic Pathology

RAS mutation patterns arise from tissue-specific responses to distinct oncogenic signaling

January 01, 2021

A Comparative Oncology Drug Discovery Pipeline to Identify and Validate New Treatments for Osteosarcoma.

November 11, 2020 Cancers

Coagulopathy Characterized by Rotational Thromboelastometry in a Porcine Pediatric ECMO Model.

September 01, 2020 Journal of Extra Corporeal Technology

Antibiotic eluting poly(ester urea) films for control of a model cardiac implantable electronic device infection.

July 15, 2020 Acta Biomater

Comparisons of Infant and Adult Mice Reveal Age Effects for Liver Depot Gene Therapy in Pompe Disease.

June 12, 2020 Molecular Therapy Methods & Clinical Development

Targeting PD-L1 Initiates Effective Antitumor Immunity in a Murine Model of Cushing Disease.

March 01, 2020 Clinical Cancer Research

Subglottic Cryotherapy: A Pilot Study in New Zealand White Rabbits.

March 01, 2020 Otolaryngology Head and Neck Surgery : Official Journal of American Academy of Otolaryngology Head and Neck Surgery

Soft Tissue Anchoring Performance, Biomechanical Properties, and Tissue Reaction of a New Hernia Mesh Engineered to Address Hernia Occurrence and Recurrence.

December 01, 2019 Journal of Medical Devices

Salmeterol with Liver Depot Gene Therapy Enhances the Skeletal Muscle Response in Murine Pompe Disease.

July 01, 2019 Hum Gene Ther

Author Correction: Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors.

March 01, 2019 Nat Med

miR-34a is a microRNA safeguard for Citrobacter-induced inflammatory colon oncogenesis.

December 13, 2018 Elife

Pathology Study Design, Conduct, and Reporting to Achieve Rigor and Reproducibility in Translational Research Using Animal Models.

December 01, 2018 Ilar J

An Introduction to Pathology in Biomedical Research: A Mission-Critical Specialty for Reproducibility and Rigor in Translational Research.

December 01, 2018 Ilar J

Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors.

September 01, 2018 Nat Med

Evolutionarily Conserved and Divergent Roles of Unfolded Protein Response (UPR) in the Pathogenic Cryptococcus Species Complex.

May 25, 2018 Scientific Reports

Distinct Angiogenic Changes during Carcinogenesis Defined by Novel Label-Free Dark-Field Imaging in a Hamster Cheek Pouch Model.

December 15, 2017 Cancer Res

The Role of the IACUC in the Design and Conduct of Animal Experiments that Contribute to Translational Success.

July 01, 2017 Ilar J

Targeting the histone methyltransferase G9a activates imprinted genes and improves survival of a mouse model of Prader-Willi syndrome.

February 01, 2017 Nat Med

HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism.

December 15, 2016 J Immunol

Current concepts of Harm-Benefit Analysis of Animal Experiments - Report from the AALAS-FELASA Working Group on Harm-Benefit Analysis - Part 1.

June 01, 2016 Laboratory Animals

Recommendations for Addressing Harm-Benefit Analysis and Implementation in Ethical Evaluation - Report from the AALAS-FELASA Working Group on Harm-Benefit Analysis - Part 2.

June 01, 2016 Laboratory Animals

Recommendations for minimum information for publication of experimental pathology data: MINPEPA guidelines.

January 01, 2016 J Pathol

Isolation and characterization of a novel Helicobacter species, Helicobacter jaachi sp. nov., from common marmosets (Callithrix jaachus).

September 01, 2015 J Med Microbiol

The future of preclinical animal models in pharmaceutical discovery and development: a need to bring in cerebro to the in vivo discussions.

January 01, 2015 Toxicol Pathol

the Toxicology Studies of Cobalt Metal (CASRN 7440-48-4) in F344/N Rats and B6C3F1/N Mice and Toxicology and Carcinogenesis Studies of Cobalt Metal in F344/NTac Rats and B6C3F1/N Mice (Inhalation Studies)

January 01, 2014

ICLAS Working Group on Harmonization: international guidance concerning the production care and use of genetically-altered animals.

July 01, 2013 Laboratory Animals

Meeting report: Urinary Pathology; sixth Research Triangle Park Rodent Pathology Course.

May 01, 2013 Vet Pathol

Environmental estrogens differentially engage the histone methyltransferase EZH2 to increase risk of uterine tumorigenesis.

April 01, 2012 Mol Cancer Res

Non-neoplastic and neoplastic pleural endpoints following fiber exposure.

January 01, 2011 J Toxicol Environ Health B Crit Rev

Guidelines for the welfare and use of animals in cancer research.

May 25, 2010 Br J Cancer

Pleural effects of indium phosphide in B6C3F1 mice: nonfibrous particulate induced pleural fibrosis.

December 01, 2009 Exp Lung Res

Inhaled carbon nanotubes reach the subpleural tissue in mice.

November 01, 2009 Nat Nanotechnol

Early onset of spontaneous renal preneoplastic and neoplastic lesions in young conventional rats in toxicity studies.

June 01, 2007 Toxicologic Pathology

Tumor-specific efficacy of transforming growth factor-beta RI inhibition in Eker rats.

May 15, 2007 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

NTP Technical Report on the Toxicity Studies of Wy-14,643 (CAS No. 50892-23-4) Administered in Feed to Sprague-Dawley Rats, B6C3F1Mice, and Syrian Hamsters

January 01, 2007

Analysis of renal cell transformation following exposure to trichloroethene in vivo and its metabolite S-(dichlorovinyl)-L-cysteine in vitro.

July 05, 2006 Toxicology

What's your diagnosis? Lethargy and hind limb paralysis in a day-23 timed pregnant rat.

February 01, 2006 Lab Animal

Preparation of animals for use in the laboratory: issues and challenges for the Institutional Animal Care and Use Committee (IACUC).

January 01, 2006 Ilar Journal

The art and science of introducing animals to the research environment.

January 01, 2006 Ilar Journal

Conditional expression of the mutant Ki-rasG12C allele results in formation of benign lung adenomas: development of a novel mouse lung tumor model.

December 01, 2005 Carcinogenesis

Mimetics of caloric restriction include agonists of lipid-activated nuclear receptors.

October 29, 2004 The Journal of Biological Chemistry

Induction of ERK1/2 and histone H3 phosphorylation within the outer stripe of the outer medulla of the Eker rat by 2,3,5-tris-(glutathion-S-yl)hydroquinone.

August 01, 2004 Toxicological Sciences

Emission-particle-induced ventilatory abnormalities in a rat model of pulmonary hypertension.

June 01, 2004 Environmental Health Perspectives

Nasal toxicity of manganese sulfate and manganese phosphate in young male rats following subchronic (13-week) inhalation exposure.

June 01, 2004 Inhalation Toxicology

Susceptibility to vascular neoplasms but no increased susceptibility to renal carcinogenesis in Vhl knockout mice.

March 01, 2004 Carcinogenesis

Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles.

February 01, 2004 Toxicological Sciences

Emmission-particle-induced ventilatory abnormalities in a rat model of pulmonary hypertension

January 01, 2004 Environmental Health Perspectives

Osteopontin expression in particle-induced lung disease.

January 01, 2004 Experimental Lung Research

Laboratory animal science issues in the design and conduct of studies with endocrine-active compounds.

January 01, 2004 Ilar Journal

Uterine leiomyoma in the Eker rat: a unique model for important diseases of women.

December 01, 2003 Genes, Chromosomes & Cancer

Variations in Prkdc and susceptibility to benzene-induced toxicity in mice.

October 01, 2003 Toxicological Sciences

Soluble ICAM-1, MCP-1, and MIP-2 protein secretion by rat pleural mesothelial cells following exposure to amosite asbestos.

July 01, 2003 Experimental Lung Research

Pleural dosimetry and pathobiological responses in rats and hamsters exposed subchronically to MMVF 10a fiberglass.

July 01, 2003 Toxicological Sciences

Ultrafine carbon black particles enhance respiratory syncytial virus-induced airway reactivity, pulmonary inflammation, and chemokine expression.

April 01, 2003 Toxicological Sciences

Male mice deficient in microsomal epoxide hydrolase are not susceptible to benzene-induced toxicity.

April 01, 2003 Toxicological Sciences

Effect of preexposure to ultrafine carbon black on respiratory syncytial virus infection in mice.

April 01, 2003 Toxicological Sciences

Genetic susceptibility to benzene-induced toxicity: role of NADPH: quinone oxidoreductase-1.

March 01, 2003 Cancer Research

Polycystic kidney disease as a result of loss of the tuberous sclerosis 2 tumor suppressor gene during development.

February 01, 2003 The American Journal of Pathology

IARC monographs on the evaluation of carcinogenic risks to humans: Man-made vitreous fibres

November 06, 2002

Long-term pulmonary responses of three laboratory rodent species to subchronic inhalation of pigmentary titanium dioxide particles.

November 01, 2002 Toxicological Sciences

Cell proliferation is insufficient, but loss of tuberin is necessary, for chemically induced nephrocarcinogenicity.

August 01, 2002 American Journal of Physiology. Renal Physiology

Chloroform inhalation exposure conditions necessary to initiate liver toxicity in female B6C3F1 mice.

April 01, 2002 Toxicological Sciences

Combined effects of dietary phytoestrogen and synthetic endocrine-active compound on reproductive development in Sprague-Dawley rats: genistein and methoxychlor.

March 01, 2002 Toxicological Sciences

Use of short-term assays to evaluate the potential toxicity of two new biosoluble glasswool fibers.

March 01, 2002 Inhalation Toxicology

NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF o-NITROTOLUENE (CAS NO. 88-72-2) IN F344/N RATS AND B6C3F1 MICE (FEED STUDIES)

January 01, 2002

The effect of chronic progressive nephropathy on the incidence of renal tubule cell neoplasms in control male F344 rats.

January 01, 2002 Toxicologic Pathology

Nephrotoxicity and hepatotoxicity induced by inhaled bromodichloromethane in wild-type and p53-heterozygous mice.

December 01, 2001 Toxicological Sciences

Use of genetically modified mouse models for evaluation of carcinogenic risk: considerations for the laboratory animal scientist.

October 01, 2001 Comparative Medicine

Acute pulmonary toxicity of particulate matter filter extracts in rats: coherence with epidemiologic studies in Utah Valley residents.

June 01, 2001 Environmental Health Perspectives

alpha 2u-Globulin nephropathy, renal cell proliferation, and dosimetry of inhaled tert-butyl alcohol in male and female F-344 rats.

May 01, 2001 Toxicological Sciences

Tuberin-dependent membrane localization of polycystin-1: a functional link between polycystic kidney disease and the TSC2 tumor suppressor gene.

April 01, 2001 Molecular Cell

Acute pulmonary toxicity of particulate matter filter extracts in rats: Coherence with epidemiologic studies in Utah valley residents

January 01, 2001 Environmental Health Perspectives

Î±2u-Globulin nephropathy, renal cell proliferation, and dosimetry of inhaled tert-butyl alcohol in male and female F-344 rats

January 01, 2001 Toxicological Sciences

Carcinogenicity of a nephrotoxic metabolite of the "nongenotoxic" carcinogen hydroquinone.

January 01, 2001 Chemical Research in Toxicology

Mutagenicity and carcinogenicity of biological reactive intermediate's derived from a "non-genotoxic" carcinogen.

January 01, 2001 Advances in Experimental Medicine and Biology

Advances in uterine leiomyoma research: conference overview, summary, and future research recommendations.

October 01, 2000 Environmental Health Perspectives

Promotion by sodium barbital induces early development but does not increase the multiplicity of hereditary renal tumors in Eker rats

August 01, 2000 Carcinogenesis

Promotion by sodium barbital induces early development but does not increase the multiplicity of hereditary renal tumors in Eker rats.

August 01, 2000 Carcinogenesis

Preclinical Evidence for Therapeutic Efficacy of Selective Estrogen receptor Modulators for Uterine Leiomyoma

July 01, 2000 Journal of the Society for Gynecologic Investigation

Protein Carbonyls in Bronchoalveolar Lavage Fluid in Mice, Rats and Hamsters Following Inhalation of Pigmentary Titanium Dioxide Particles.

January 01, 2000 Inhalation Toxicology

Comparison of Selected Pulmonary Responses of Rats, Mice, and Syrian Golden Hamsters to Inhaled Pigmentary Titanium Dioxide.

January 01, 2000 Inhalation Toxicology

Advances in uterine leiomyoma research: Conference overview, summary, and future research recommendations

January 01, 2000 Environmental Health Perspectives

Preclinical evidence for therapeutic efficacy of selective estrogen receptor modulators for uterine leiomyoma.

January 01, 2000 Journal of the Society for Gynecologic Investigation

Mesotheliomas induced in rats by the fibrous mineral erionite are independent from p53 alterations.

December 01, 1999 Cancer Letters

Metabolism of chloroform by cytochrome P450 2E1 is required for induction of toxicity in the liver, kidney, and nose of male mice.

October 15, 1999 Toxicology and Applied Pharmacology

Studies on the inhalation toxicology of two fiberglasses and amosite asbestos in the Syrian golden hamster. Part II. Results of chronic exposure.

September 01, 1999 Inhalation Toxicology

Studies on the inhalation toxicology of two fiberglasses and amosite asbestos in the syrian golden hamster. Part I. Results of a subchronic study and dose selection for a chronic study.

September 01, 1999 Inhalation Toxicology

Comparison of pulmonary and pleural responses of rats and hamsters to inhaled refractory ceramic fibers.

May 01, 1999 Toxicological Sciences

NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF 60-HZ MAGNETIC FIELDS IN F344/N RATS AND B6C3F1 MICE (WHOLE-BODY EXPOSURE STUDIES)

January 01, 1999

Estrogen treatment enhances hereditary renal tumor development in Eker rats.

November 01, 1998 Carcinogenesis

Redistribution and enhanced protein kinase C-mediated phosphorylation of alpha- and gamma-adducin during renal tumor progression.

May 01, 1998 Cell Growth & Differentiation : the Molecular Biology Journal of the American Association for Cancer Research

Long-term mutagenicity studies with chloroform and dimethylnitrosamine in female lacI transgenic B6C3F1 mice.

January 01, 1998 Environmental and Molecular Mutagenesis

Experimental approaches for studies of particulate matter: the case for stronger consideration of dosimetric and exposure issues.

January 01, 1998 Experimental Lung Research

Comparison of pleural responses of rats and hamsters to subchronic inhalation of refractory ceramic fibers.

September 01, 1997 Environmental Health Perspectives

Chronic inhalation study of fiber glass and amosite asbestos in hamsters: twelve-month preliminary results.

September 01, 1997 Environmental Health Perspectives

Comparison of pleural responses of rats and hamsters to subchronic inhalation of refractory ceramic fibers.

September 01, 1997 Environmental Health Perspectives

Effects of immobilization restraint on Syrian golden hamsters.

August 01, 1997 Laboratory Animal Science

Altered expression of transforming growth factor-alpha: an early event in renal cell carcinoma development.

July 01, 1997 Molecular Carcinogenesis

Pharmacokinetics of methanol and formate in female cynomolgus monkeys exposed to methanol vapors.

June 01, 1997 Research Report (Health Effects Institute)

Chrysotile asbestos and H2O2 increase permeability of alveolar epithelium.

January 01, 1997 Experimental Lung Research

Rodent model of reproductive tract leiomyomata: characterization and use in preclinical therapeutic studies.

January 01, 1997 Progress in Clinical and Biological Research

Pulmonary and pleural leukocytes from F344 rats produce elevated levels of fibronectin following inhalation of refractory ceramic fibers.

November 01, 1996 Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Fur Toxikologische Pathologie

Use of lung toxicity and lung particle clearance to estimate the maximum tolerated dose (MTD) for a fiber glass chronic inhalation study in the rat.

July 01, 1996 Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology

Pulmonary and pleural responses in Fischer 344 rats following short-term inhalation of a synthetic vitreous fiber. I. Quantitation of lung and pleural fiber burdens.

March 01, 1996 Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology

Pulmonary and pleural responses in Fischer 344 rats following short-term inhalation of a synthetic vitreous fiber. II. Pathobiologic responses.

March 01, 1996 Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology

Renal cell carcinoma development in the rat independent of alterations at the VHL gene locus.

February 01, 1996 Molecular Carcinogenesis

TOXICOLOGY AND CARCINOGENESIS STUDIES OF NICKEL SUBSULFIDE (CAS NO. 12035-72-2) IN F344/N RATS AND B6C3F1 MICE (INHALATION STUDIES)

January 01, 1996

TOXICOLOGY AND CARCINOGENESIS STUDIES OF NICKEL SULFATE HEXAHYDRATE (CAS NO. 10101-97-0) IN F344/N RATS AND B6C3F1 MICE (INHALATION STUDIES)

January 01, 1996

Pulmonary and Pleural Responses in Fischer 344 Rats Following Short-Term Inhalation of a Synthetic Vitreous Fiber

January 01, 1996 Toxicological Sciences

Pulmonary and Pleural Responses in Fischer 344 Rats Following Short-Term Inhalation of a Synthetic Vitreous Fiber

January 01, 1996 Toxicological Sciences

Hereditary renal cell carcinoma in the Eker rat: a unique animal model for the study of cancer susceptibility.

December 01, 1995 Toxicology Letters

Estrogen stimulation and tamoxifen inhibition of leiomyoma cell growth in vitro and in vivo.

November 01, 1995 Endocrinology

Allelic loss at the tuberous sclerosis 2 locus in spontaneous tumors in the Eker rat.

September 01, 1995 Molecular Carcinogenesis

Expression of insulin-like growth factor II in spontaneously immortalized rat mesothelial and spontaneous mesothelioma cells: a potential autocrine role of insulin-like growth factor II.

August 15, 1995 Cancer Research

Preneoplastic and neoplastic lesions of rat hereditary renal cell tumors express markers of proximal and distal nephron.

July 01, 1995 Veterinary Pathology

Estrogen/antiestrogen responsiveness in an in vivo/in vitro model for myometrial tumorigenesis.

June 12, 1995 Annals of the New York Academy of Sciences

Rodent model of reproductive tract leiomyomata. Clinical and pathological features.

June 01, 1995 The American Journal of Pathology

Rodent model of reproductive tract leiomyomata. Establishment and characterization of tumor-derived cell lines.

June 01, 1995 The American Journal of Pathology

Proposed IACUC guidelines for the review of rodent toxicology studies.

May 01, 1995 Contemporary Topics in Laboratory Animal Science

p53 status in spontaneous and dimethylnitrosamine-induced renal cell tumors from rats.

April 01, 1995 Molecular Carcinogenesis

Autocrine growth stimulation by transforming growth factor alpha in asbestos-transformed rat mesothelial cells.

February 01, 1995 Cancer Research

Erratum: Carcinogenicity and Toxicity of inhaled nitrobenzene in B6C3F1 mice and F344 and CD rats (Fundamental and Applied Toxicology (1994) Vol. 22, Number 3 (pp. 328-340))

January 01, 1995 Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology

Toxicity Studies of Cadmium Oxide Administered by Inhalation to F344/N Rats and B6C3F1 Mice

January 01, 1995

Toxicity Studies of Dibutyl Phthalate Administered in Feed to F344/N Rats and B6C3F1 Mice

January 01, 1995

Mechanisms of fiber-induced diseases: implications for the safety evaluation of synthetic vitreous fibers.

December 01, 1994 Regulatory Toxicology and Pharmacology

Increased susceptibility to in vitro transformation of cells carrying the Eker tumor susceptibility mutation.

October 01, 1994 Carcinogenesis

Mesothelial cell proliferation induced by intrapleural instillation of man-made fibers in rats and hamsters.

July 01, 1994 Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology

Wilms' tumor suppressor gene expression in rat and human mesothelioma.

June 15, 1994 Cancer Research

Carcinogenicity and toxicity of inhaled nitrobenzene in B6C3F1 mice and F344 and CD rats.

April 01, 1994 Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology

Atypical tubule hyperplasia and renal tubule tumors in conventional rats on 90-day toxicity studies.

January 01, 1994 Toxicologic Pathology

Pleural lesions in Syrian golden hamsters and Fischer-344 rats following intrapleural instillation of man-made ceramic or glass fibers.

January 01, 1994 Toxicologic Pathology

Carcinogenicity of inhaled benzene in CBA mice.

May 01, 1993 Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology

Suppression of tumorigenicity of A549 lung adenocarcinoma cells by human chromosomes 3 and 11 introduced via microcell-mediated chromosome transfer.

January 01, 1993 Molecular Carcinogenesis

Hereditary renal cell carcinoma in the Eker rat: a rodent familial cancer syndrome.

December 01, 1992 The Journal of Urology

Antioxidant defense mechanisms in cultured pleural mesothelial cells.

July 01, 1992 American Journal of Respiratory Cell and Molecular Biology

Predisposition to renal cell carcinoma due to alteration of a cancer susceptibility gene.

March 27, 1992 Science (New York, N.Y.)

Characterization of platelet-derived growth factor and platelet-derived growth factor receptor expression in asbestos-induced rat mesothelioma.

January 15, 1992 Cancer Research

OXIDANTS AND ANTIOXIDANTS IN ALVEOLAR EPITHELIAL TYPE-II CELLS - INSITU, FRESHLY ISOLATED, AND CULTURED-CELLS

January 01, 1992 The American Journal of Physiology

Oxidants and antioxidants in alveolar epithelial type II cells: in situ, freshly isolated, and cultured cells.

January 01, 1992 The American Journal of Physiology

Cytochrome P-450- and glutathione-associated enzyme activities in freshly isolated enriched lung cell fractions from beta-naphthoflavone-treated male F344 rats.

January 01, 1992 Toxicology

Possible cellular and molecular mechanisms for asbestos carcinogenicity.

January 01, 1992 American Journal of Industrial Medicine

Cytogenetic and molecular correlates between rodent and human renal cell carcinoma.

January 01, 1992 Progress in Clinical and Biological Research

Hereditary renal cell carcinoma in the rat associated with nonrandom loss of chromosomes 5 and 6.

August 15, 1991 Cancer Research

Trisomy of rat chromosome 1 associated with mesothelial cell transformation.

August 01, 1991 Cancer Research

HYDROGEN-PEROXIDE PRODUCTION BY ALVEOLAR TYPE-II CELLS, ALVEOLAR MACROPHAGES, AND ENDOTHELIAL-CELLS

August 01, 1991 The American Journal of Physiology

Covalent binding of inhaled formaldehyde to DNA in the respiratory tract of rhesus monkeys: pharmacokinetics, rat-to-monkey interspecies scaling, and extrapolation to man.

August 01, 1991 Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology

Hydrogen peroxide production by alveolar type II cells, alveolar macrophages, and endothelial cells.

August 01, 1991 The American Journal of Physiology

Altered expression of transforming growth factor-alpha in hereditary rat renal cell carcinoma.

June 01, 1991 Cancer Research

Primary optic nerve meningiomas in F344 rats.

January 01, 1991 Veterinary Pathology

Co-culture of primary pulmonary cells to model alveolar injury and translocation of proteins.

December 01, 1990 In Vitro Cellular & Developmental Biology Animal

Expression of growth factor and growth factor receptor RNA in rat pleural mesothelial cells in culture.

September 01, 1990 Experimental Cell Research

Infectious diseases of the upper respiratory tract: implications for toxicology studies.

April 01, 1990 Environmental Health Perspectives

Infectious diseases of the upper respiratory tract: implications for toxicology studies.

April 01, 1990 Environmental Health Perspectives

Clinical and morphologic features of post-traumatic ocular sarcomas in cats.

January 01, 1990 Veterinary Pathology

The use of tracheal implants in toxicology and carcinogenesis research.

January 01, 1990 Toxicology

Effects of formaldehyde gas on the respiratory tract of rhesus monkeys. Pathology and cell proliferation.

March 01, 1989 The American Journal of Pathology

Development of a tracheal implant xenograft model to expose human bronchial epithelial cells to toxic gases.

January 01, 1989 Toxicologic Pathology

Urologic syndrome associated with wire caging in AKR mice.

October 01, 1988 Laboratory Animal Science

Formaldehyde concentrations in the blood of rhesus monkeys after inhalation exposure.

August 01, 1988 Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association

Effect of a purified diet on dystrophic cardiac calcinosis in mice.

August 01, 1988 Laboratory Animal Science

A nylon ball device for primate environmental enrichment.

August 01, 1988 Laboratory Animal Science

Carcinogen-induced unscheduled DNA synthesis in xenotransplanted human tracheobronchial epithelium: comparison with rat tracheal epithelium.

March 01, 1988 Carcinogenesis

High mortality with severe dystrophic cardiac calcinosis in C3H/OUJ mice fed high fat purified diets.

March 01, 1988 Veterinary Pathology

Pathologic changes associated with fatal Plasmodium falciparum infection in the Bolivian squirrel monkey (Saimiri sciureus boliviensis).

July 01, 1987 The American Journal of Tropical Medicine and Hygiene

Lymphocyte activation, cell-mediated cytotoxicity and their relationship to dietary fat-enhanced mammary tumorigenesis in C3H/OUJ mice.

May 01, 1987 The Journal of Nutrition

Diagnostic exercise: eye lesions in rats.

April 01, 1987 Laboratory Animal Science

Effects of an insecticidal dip containing d-limonene in the cat.

October 15, 1986 Journal of the American Veterinary Medical Association

Diagnostic exercise: lingual growths in rabbits.

October 01, 1986 Laboratory Animal Science

Experimental Babesia bovis infection in Holstein calves.

September 01, 1986 Veterinary Pathology

Multicentric nerve sheath fibrosarcomas of multiple cranial nerve roots in two dogs.

April 01, 1986 Journal of the American Veterinary Medical Association

Sudden death in training and racing Thoroughbred horses.

December 15, 1985 Journal of the American Veterinary Medical Association

Use of in vitro cytotoxicity to rank ocular irritation of six surfactants.

January 01, 1985 Alternative methods in toxicology.

Lymphosarcoma as the cause of ataxia in a horse.

June 15, 1984 Journal of the American Veterinary Medical Association

Porcine necrotizing staphylococcal endometritis.

January 01, 1981 Veterinary Pathology

Cutaneous herpes simplex virus infection of guinea pigs as a model for antiviral chemotherapy.

March 04, 1977 Annals of the New York Academy of Sciences

Kidney and Urinary Bladder

2022 Pathology of Genetically Engineered and Other Mutant Mice

Issues in Laboratory Animal Science That Impact Toxicologic Pathology

2021 Haschek and Rousseaux's Handbook of Toxicologic Pathology: Volume 1: Principles and Practice of Toxicologic Pathology

Animal Care and Use in Toxicity Testing

2018 Comprehensive Toxicology: Third Edition

The use of the marmoset in toxicity testing and nonclinical safety assessment studies

2018 The Common Marmoset in Captivity and Biomedical Research

Issues in Laboratory Animal Science

2013 Haschek and Rousseaux's Handbook of Toxicologic Pathology

Issues in Laboratory Animal Science

2013 Haschek and Rousseaux's Handbook of Toxicologic Pathology, Third Edition: Volume 1-3

Animal Care and Use in Toxicity Testing

2010 Comprehensive Toxicology, Second Edition

Neoplastic Disease

2006 The Laboratory Rat

Euthanasia and Necropsy

2006 The Laboratory Rat

United States guidelines and regulations in animal experimentation

2006 In Vivo Models of Inflammation

Euthanasia and Necropsy

2005 The Laboratory Rat, Second Edition

Neoplastic Disease

2005 The Laboratory Rat, Second Edition

Experimental Ocular Oncology: Animal Models

2002

Hereditary Renal Cell Adenoma and Carcinoma, Rat

1998 Urinary System

Melanoma of the Uvea, Rat

1991 Eye and Ear

Retinoblastoma, Experimental, Rat and Hamster

1991 Eye and Ear

Longitudinal Analysis in A HNF4A^ÎIEC Mouse Colitis Model Reveals that Preclinical Flaring is Associated with Increased Akkermansia muciniphila Levels in the Gut Microbiome

2021 Gastroenterology

Abstract 5243: Averting tumor growth in rodent breast cancer models with a liquid ablation approach

2020 Cancer Research

Salmeterol with Liver Depot Gene Therapy Reversed Biochemical and Autophagic Abnormalities of Skeletal Muscle in Pompe Disease

2019 Molecular Therapy

Long-term complications of glycogen storage disease type Ia in the canine model treated with gene replacement therapy.

2018 J Inherit Metab Dis

Comparison of the pulmonary responses to inhaled pigmentary and ultrafine titanium dioxide particles in the rat, mouse and hamster

2002 Annals of Occupational Hygiene

Chronic Inhalation Study of Fiber Glass and Amosite Asbestos in Hamsters: Twelve-Month Preliminary Results

1997 Environmental Health Perspectives

Mechanisms of fiber-induced diseases: Implications for the safety evaluation of synthetic vitreous fibers

1994 Regulatory Toxicology and Pharmacology

MECHANISMS OF FIBER-INDUCED DISEASES - IMPLICATIONS FOR THE SAFETY EVALUATION OF SYNTHETIC VITREOUS FIBERS

1994 Regulatory Toxicology and Pharmacology

Species-specific PDGF expression in mesothelioma

1993 European Respiratory Review

UNSCHEDULED DNA-SYNTHESIS (UDS) IN XENOGRAFTS CONTAINING RAT OR HUMAN RESPIRATORY EPITHELIAL-CELLS

1987 Proceedings of the American Association for Cancer Research

jeffrey.everitt@duke.edu

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