Paul Martin
Professor of Pediatrics
Overview
For most of my career in Pediatric Hematology/Oncology I have focused on the use of stem cell transplant for the treatment of pediatric leukemias (ALL, AML, CML and JMML) and other non-malignant blood disorders, such as sickle cell disease, hemaphagocytic disorders, Wiskott-Aldrich, aplastic anemia, Diamond-Blackfan Anemia, as well as inherited metabolic diseases. In addition to focusing on determining the best use of stem cell transplants for these disorders, I have also been involved in clinical research investigating the prevention and treatment of transplant related morbidity, particularly veno-occlusive disease of the liver, infections and diffuse alveolar hemorrhage. As study chair for the Children's Oncology Group protocol 9904, I was involved in the development, implementation and analysis of a large, international frontline study of childhood acute lymphoblastic leukemia. Results from this study show that a significant number of children with certain favorable cytogenetic abnormalities in their leukemic cells and who have a rapid response to their initial chemotherapy can expect to have a >95% chance of cure when treated with relatively low intensity chemotherapy.
I have concentrated on providing high quality care for high risk leukemia patients who require high intensity therapies, such as stem cell transplant and immunotherapy. As a member of the Pediatric Transplant and Cellular Therapy Division I provide clinical care for these patients. As a member of various cooperative groups and local PI for several drug trials, I have worked to provide better care and more specific therapies for the toxicities associated with stem cell transplant.
I have also collaborated with the Pediatric Immunology Division to provide a life-saving therapy for a small group of patients with thymic dysfunction, which causes severe immunodeficiency. Our clinical team now provides support during these patients hospital admissions for donor thymus tissue implantation. We once again achieved a new record for the number of implanted patients during the 2022-2023 academic year.
Positions
Professor of Pediatrics in the School of Medicine
2021 School of Medicine
Member of the Duke Cancer Institute in the School of Medicine
1996 School of Medicine
Education
M.D. 1987
1987 Washington University in St. Louis
Ph.D. 1987
1987 Washington University in St. Louis
Intern, Pediatrics
1988 Yale University
Resident, Pediatrics
1989 Yale University
Fellow, Pediatric Hematology/Oncology, Pediatrics
1992 Yale University
Publications, Grants & Awards
- Grants (9)
- Academics Articles (123)
- Conference Pages (88)
National Institutes of Health
National Marrow Donor Program
Children's Healthcare of Atlanta
Novartis Pharmaceuticals Corporation
Children's Hospital Los Angeles
MedImmune, Inc.
National Institutes of Health
Am J Hematol
Blood Adv
Journal of Clinical Oncology
J Natl Compr Canc Netw
Open Forum Infectious Diseases
Bone Marrow Transplant
Pediatr Blood Cancer
Nature Reviews. Clinical Oncology
Nature Reviews. Clinical Oncology
Pediatr Transplant
J Natl Cancer Inst
Pediatr Blood Cancer
Biol Blood Marrow Transplant
Open Forum Infectious Diseases
Pediatr Blood Cancer
Open Forum Infectious Diseases
Biol Blood Marrow Transplant
Clinical Pharmacology and Therapeutics
Biol Blood Marrow Transplant
Pediatr Blood Cancer
Biol Blood Marrow Transplant
Nature Reviews. Clinical Oncology
Cardiol Young
Bone Marrow Transplant
Biol Blood Marrow Transplant
Biol Blood Marrow Transplant
Journal of Clinical Oncology
The New England Journal of Medicine
Biol Blood Marrow Transplant
Biol Blood Marrow Transplant
Pediatr Blood Cancer
Biol Blood Marrow Transplant
Journal of Clinical Oncology
Pediatr Blood Cancer
Lancet Oncol
Molecular Genetics and Metabolism Reports
Biol Blood Marrow Transplant
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
J Pediatr Oncol Nurs
J Natl Cancer Inst
Biol Blood Marrow Transplant
Pediatr Infect Dis J
Expert Review of Hematology
Journal of Clinical Oncology
J Nurs Care Qual
American Family Physician
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Journal of Clinical Oncology
Biol Blood Marrow Transplant
Biol Blood Marrow Transplant
Biol Blood Marrow Transplant
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biol Blood Marrow Transplant
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Journal of Clinical Oncology
Pediatr Blood Cancer
Pediatric Blood & Cancer
Pediatric Infectious Disease Journal
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Respiratory Care Clinics of North America
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Cytometry. Part B, Clinical Cytometry
Journal of Pediatric Hematology/Oncology
The New England Journal of Medicine
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Journal of Bone and Mineral Research
Pediatric Critical Care Medicine
Pediatric Infectious Disease Journal
Critical Care Medicine
Annals of Neurology
Journal of Pediatric Surgery
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Bone Marrow Transplantation
Current Opinion in Pediatrics
Stem Cells (Dayton, Ohio)
Bone Marrow Transplantation
Leukemia Research
Journal of Pediatric Hematology/Oncology
Seminars in Perinatology
Science (New York, N.Y.)
Methods in Enzymology
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Cancer Cell
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Clinical Lymphoma, Myeloma & Leukemia
Haematologica the Hematology Journal
Haematologica the Hematology Journal
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Bone Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Offices & Contact
Durham, NC
27705 Box 102502 Med Ctr
Durham, NC
27710