Stacy Horner
Associate Professor in Integrative Immunobiology
Overview
Studying the RNA biology, cell biology, and immunology of RNA virus infection
Our lab studies the molecular mechanisms that regulate RNA virus-host interactions. We focus primarily on viruses in the Flaviviridae family of viruses, including dengue virus (DENV), Zika virus (ZIKV), and hepatitis C virus (HCV). Our research is focused on defining (1) how these viruses replicate, (2) the mechanisms that regulate antiviral innate immunity to these viruses, and (3) RNA regulatory controls to both of these processes. Our lab has pioneered approaches to how the RNA modification m6A regulates viral infection, antiviral innate immunity and the host response to virus infection. Our long-term goal is to discover the necessary mechanistic and functional information to guide future development of new strategies for virus treatment and prevention.
Positions
Associate Professor in Integrative Immunobiology in the School of Medicine
2022 School of Medicine
Associate Professor of Medicine in the School of Medicine
2021 School of Medicine
Associate Professor of Cell Biology in the School of Medicine
2022 School of Medicine
Associate Professor of Molecular Genetics and Microbiology in the School of Medicine
2022 School of Medicine
Associate of the Duke Initiative for Science & Society in the Institutes and Provost's Academic Units
2018 Institutes and Provost's Academic Units
Member of the Duke Cancer Institute in the School of Medicine
2014 School of Medicine
Education
Ph.D. 2007
2007 Yale University
Publications, Grants & Awards
- Grants (26)
- Academics Articles (63)
- Book Sections (2)
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
American Cancer Society, Inc.
National Institutes of Health
National Institutes of Health
Burroughs Wellcome Fund
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
American Cancer Society, Inc.
National Institutes of Health
Hartwell Foundation
Burroughs Wellcome Fund
Weill Medical College of Cornell University
National Institutes of Health
American Heart Association
National Institutes of Health
National Institutes of Health
National Institutes of Health
Ribometrix LLC
National Institutes of Health
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
J Mol Biol
Science Immunology
Trends in Biochemical Sciences
Brief Funct Genomics
Nature Communications
Scientific Reports
Science Advances
The Journal of Biological Chemistry
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
Cell Host Microbe
Nature Communications
Plos Pathog
Curr Opin Virol
Methods Mol Biol
Curr Opin Microbiol
Journal of Molecular Biology
Future Virology
Cell Host Microbe
Proc Natl Acad Sci U S A
J Interferon Cytokine Res
Journal of Virology
Journal of Virology
Traffic (Copenhagen, Denmark)
Chronic Hepatitis B and C: Basic Science to Clinical Applications
Beyond Apoptosis: Cellular Outcomes of Cancer Therapy
Offices & Contact
Durham, NC
27710