Aims
- Characterize the molecular and genetic processes that drive cancer initiation.
- Define cellular signaling and metabolic mechanisms that promote tumor development, recurrence, and metastasis.
- Train the next generation of basic cancer researchers through robust mentoring and career development.
The Cancer Biology Program investigates the core molecular and cellular processes that drive cancer initiation, progression, metastasis, and treatment resistance. Scientists across multiple disciplines study DNA replication and repair, gene regulation, cell signaling, epigenetics, tumor metabolism, the tumor microenvironment, and virus‑associated cancers, using advanced tools such as single‑cell and spatial profiling, engineered cell and tissue systems, imaging platforms, and computational modeling. These integrated approaches connect basic discoveries with new opportunities for prevention, diagnosis, and therapy, while partnerships with community collaborators help ensure the research reflects regional cancer priorities.
Training and mentorship are central to the program’s mission. Students and postdoctoral researchers participate in structured career development activities, including mentoring, skills workshops, journal clubs, and grant‑writing support, all reinforced by dedicated training grants. Through its scientific depth, collaborative culture, and strong commitment to cultivating future researchers, the Cancer Biology Program drives discoveries that advance understanding of cancer and support improved outcomes.