In this study, you will take a medicine called ALTA3263 by mouth every day. You will keep taking it until your cancer gets worse or until you need to stop because of strong or frequent side effects. While you are in the study, you will go to the clinic for regular visits. During these visits, the study team will do tests to check your health and collect information for research.

Advanced Solid Tumors With KRAS
Mutations

People can join this study if they are at least 18 years old and have a solid tumor cancer that has a specific change in a gene called KRAS. This change can be found in the tumor or in the blood. They must also have cancer that cannot be removed with surgery or has spread to other parts of the body.

This study is being done to learn if a new medicine called ALTA3263 is safe to use. The study will also look at both the helpful and harmful effects of the medicine when it is given in different amounts. Researchers want to understand how the drug affects the body so they can learn the best and safest dose to use in future studies.