We are doing this study to find the most effective, safe dose of an experimental drug called BHV-1530 (the study drug) for adults who have advanced or metastatic solid tumors.

Advanced or Metastatic Solid Tumors

Adults ages 18+ who:

• Have a solid tumor form of cancer
• Have disease that is locally advanced/metastatic and has not responded to therapy or come back after therapy

For more information, contact the study team at hollie.watson@duke.edu.

If you choose to join this study, you will:

• Get the study drug as an intravenous (IV) infusion every 3 weeks
• Have study visits between drug infusions that might include the following procedures: physical exams, echocardiograms, imaging scans (CT or MRI), eye exams, or tumor tissue sampling

You will get the study drug for as long as the study doctor believes that you are getting a benefit. The dose of the study drug that is given will vary depending on when you join the study.