We are doing this study to better understand how breast cancer treatment can affect the heart. In particular, we want to know if treatment with near complete estrogen deprivation (NCED) therapy has an impact on heart function.

Risk of Heart Injury in Women Receiving Therapy for Breast Cancer

Women ages 55 or younger who:

• Are premenopausal when they receive their breast cancer diagnosis
• Have Stage 1-to-3 breast cancer
• Have recently started or plan to start breast cancer treatment therapy

For more information about who can be in this study, please contact the study team at BreastCl@dm.duke.edu.

If you choose to join this study, you will:

• Have 3 heart stress tests over the course of 2 years
• Have a cardiac MRI at the beginning of the study, at the 1 year mark, and at the end of the study
• Get a CT scan at the beginning of the study and 2 years later at the end
• Have an EKG/ECG (measures the electrical signal from the heart) 3 times
• Have up to 6 blood draws throughout the study