EXCILYNT (Melanoma)
What is the Purpose of this Study?
We are doing this study to find out if surgically removing only the cancerous lymph node (known as a lymph node excision) is effective at preventing melanoma from coming back in the same area of the lymph node excision. We also want to learn more about the side effects of this type of surgery and how it can impact patients' quality of life.
What is the Condition Being Studied?
Metastatic Melanoma
Who Can Participate in the Study?
Adults ages 18+ who:
- Are diagnosed with melanoma that has spread to only one lymph node in the axilla (underarm area), groin, or iliac basin (pelvic region)
- Are able to undergo lymph node excision
- Have not had a lymph node dissection
For more information about who can join this study, please contact the study team at chandler.warren@duke.edu.
Age Group
Adults
What is Involved?
If you choose to join this study, you will have your enlarged lymph node removed during your planned cancer removal surgery. We wil keep in touch with you after this surgery to keep tabs on how you are doing. During this time, you will:
- Have blood draws
- Have physical exams
- Have imaging scans (PET/CT and MRI)
- Fill out surveys
Study Details
Full Title
Lymph Node Excision (LNEx) for Patients with Stage III Melanoma with One Clinically Positive Node: Excision of Lymph Node Trial [EXCILYNT]
Principal Investigator
Assistant Professor of Surgery
Protocol Number
IRB:
PRO00114693
NCT:
NCT05839912
Phase
Phase
II
ClinicalTrials.gov
View on ClinicalTrials.gov
Enrollment Status
OPEN TO ACCRUAL