Participants will be randomly assigned to receive either methylprednisolone before surgery or no methylprednisolone before surgery. Researchers will collect information about recovery, side effects, tests, and procedures for about 30 days after surgery. The information will be added to a research database to compare outcomes between the two groups and evaluate the effectiveness of the treatment.

Hepatectomy (liver resection)

Participants may be able to join if they are adults age 18 or older who are scheduled to undergo a major liver surgery called a hepatectomy. Researchers are studying whether receiving methylprednisolone before surgery can help reduce side effects and improve recovery after the procedure.

This study is testing whether giving methylprednisolone before surgery can reduce side effects and improve recovery after surgery. Methylprednisolone is a steroid medicine that helps reduce inflammation and calm the immune system. Researchers will compare people who receive the medication before surgery with those who do not to see if it improves outcomes.