X-PACT Immunolight (Breast Cancer, Head & Neck Cancer, Melanoma, and Sarcoma)

What is the Purpose of this Study?

We are doing this study to find out if an experimental drug and device system called X-PACT is a safe and effective treatment for various forms of cancer.

What is the Condition Being Studied?

Sarcoma, Breast Cancer, Melanoma, and Head & Neck Cancer

Who Can Participate in the Study?

Adults ages 18+ who:

  • Have soft tissue sarcoma, melanoma, breast cancer, or head and neck cancer
  • Still have cancer after treatment with the standard therapies
  • Do not have any other treatment options left

For more information about who can join this study, please contact the study team at elizabeth.sachs@duke.edu

Age Group

What is Involved?

If you join this study, you will:

  • Be injected with the study treatment (X-PACT) five times
  • Give tumor tissue
  • Have physical exams, blood draws, and urine tests
  • Have a heart scan (ECG)
  • Have imaging scans (X-Rays, MRI and/or CT)

Please visit https://www.immunolight.com/patients to learn more about the study treatment.

Study Details

Full Title
Phase 1 Study of X-PACT (X-ray Psoralen Activated Cancer Therapy) for Intra-tumoral Injection in Patients with Advanced Head and Neck Cancer, Breast Cancer, Soft Tissue Sarcoma or Melanoma
Principal Investigator
Frank H. Bassett III, M. D. Associate Professor of Orthopaedic Surgery
Protocol Number
IRB: PRO00105022
NCT: NCT04389281
Phase I
Enrollment Status