David R. Sherwood
David R. Sherwood

David R. Sherwood

Jerry G. and Patricia Crawford Hubbard Professor

Overview

The Sherwood lab is interested in understanding mechanisms that drive dynamic cellular behaviors underlying normal development and human disease. We study 1) How cells invade into tissues, 2) How stem cells interact with their niches, and 3) How cells control and interact with extracellular matrix. Our lab primarily examines C. elegans development, in which simple cellular complexity, amenability to genetics/genomics/transgenics/molecular perturbations, and evolutionary comparisons facilitates powerful insights. One particular emphasis of our work is live-cell imaging, where we watch cellular behaviors and cell-extracellular matrix interactions unfold in real-time to understand their regulation and function.  Cell invasion, stem cell regulation, and cell-matrix interactions are fundamental to development, regeneration, cancer, and aging.  Our work aims to advance our understanding of these fascinating processes and positively influence human health.

Positions

Jerry G. and Patricia Crawford Hubbard Professor in the Trinity College of Arts & Sciences

2019 Trinity College of Arts & Sciences

Professor of Biology in the Trinity College of Arts & Sciences

2017 Trinity College of Arts & Sciences

Associate Chair of the Department of Biology in the Trinity College of Arts & Sciences

2018 Trinity College of Arts & Sciences

Associate Professor in Cell Biology in the School of Medicine

2016 School of Medicine

Co-Director of the Duke Regeneration Center in the School of Medicine

2021 School of Medicine

Member of the Duke Cancer Institute in the School of Medicine

2019 School of Medicine

Education

B.A. 1990

1990 Wesleyan University

Ph.D. 1997

1997 Duke University

Publications, Grants & Awards

Offices & Contact

Box 90338
Durham, NC
27708
Duke Box 90338
Durham, NC
27708-1000