Deborah Muoio
George Barth Geller Distinguished Professor of Cardiovascular DiseaseOverview
Deb Muoio is professor in the Departments of Medicine and Pharmacology & Cancer Biology, George Barth Geller Distinguished Professor of Cardiovascular Disease, and Associate Director of the Duke Molecular Physiology Institute (DMPI). She is viewed nationally and internationally as a leader in the fields of diabetes, obesity, exercise physiology, and mitochondrial energy metabolism. Her laboratory investigates mechanisms of metabolic regulation, with emphasis on molecular events that link lifestyle factors such as over nutrition and physical inactivity to metabolic disorders, including obesity, diabetes, and heart failure. Her program features a translational approach that combines work in animal and cell-based models with human studies, using genetic engineering, molecular biology and mass spectrometry-based metabolomics and proteomics as tools to understand the interplay between mitochondrial physiology and cardiometabolic health. Her laboratory developed a sophisticated platform for deep and comprehensive assessment of mitochondrial bioenergetics and energy transduction. Her team is integrating this new platform with metabolomics, proteomics, and metabolic flux analysis to gain insights into mechanisms by which mitochondria modulate insulin action and metabolic resilience. She has published more than 120 papers in prominent journals such as Cell, Cell Metabolism, Circulation, Circulation Research, Diabetes, and JCI Insight. Dr. Muoio’s laboratory has enjoyed longstanding support from the NIDDK and NHLBI.
PhD, University of North Carolina, Chapel Hill, NC
Positions
George Barth Geller Distinguished Professor of Cardiovascular Disease in the School of Medicine
2021 School of Medicine
Professor of Medicine in the School of Medicine
2016 School of Medicine
Professor in Pharmacology and Cancer Biology in the School of Medicine
2016 School of Medicine
Member of Sarah W. Stedman Nutrition and Metabolism Center in the School of Medicine
2002 School of Medicine
Member of the Duke Cancer Institute in the School of Medicine
2013 School of Medicine
Education
Ph.D. 1999
1999 University of North Carolina - Chapel Hill
Publications, Grants & Awards
- Grants (51)
- Awards (9)
- Academics Articles (159)
- Conference Pages (17)
- Book Sections (1)
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
University of North Carolina - Chapel Hill
Wake Forest University
University of Pennsylvania
National Institutes of Health
National Institutes of Health
East Carolina University
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
Eli Lilly and Company
University of Minnesota
Augusta University
National Institutes of Health
American Heart Association
University of Pennsylvania
East Carolina University
American Heart Association
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
East Carolina University
National Institutes of Health
National Institutes of Health
National Institutes of Health
Sanford-Burnham Medical Research Institute
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
National Institutes of Health
Joslin Diabetes Center, Boston, MA
University of North Carolina - Chapel Hill
BIDMC, Division of Endocrinology, Boston, MA
University of Missouri
East Carolina University, Greenville, NC
Journal of Lipid Research
Duke University
Kern Aspen Lipid Conference
Dannon Institute of Nutrition
Cell Chem Biol
J Clin Invest
Clin J Am Soc Nephrol
Molecular Metabolism
Data in Brief
Scientific Reports
Molecular Metabolism
Jci Insight
Cell Reports
Nature Metabolism
Circulation Research
Cell Metab
Frontiers in Immunology
Cardiovasc Res
Biomaterials
Nucleic Acids Res
Am J Physiol Endocrinol Metab
Cell Reports
The Journal of Biological Chemistry
Biochemical and Biophysical Research Communications
Arthritis Research & Therapy
Biochemical and Biophysical Research Communications
Am J Physiol Heart Circ Physiol
Plos Genet
Circulation Research
Cell Metab
Cell Metab
Cell Metab
Obesity (Silver Spring, Md.)
Obesity (Silver Spring)
The Biochemical Journal
Diabetes
Nature
Circ Heart Fail
Endocrine Reviews
Journal of Pharmacology and Experimental Therapeutics
The Journal of Biological Chemistry
The American Journal of Clinical Nutrition
Circulation Research
The Journal of Biological Chemistry
American Journal of Clinical Nutrition
The American Journal of Clinical Nutrition
Jpen J Parenter Enteral Nutr
Am J Physiol Regul Integr Comp Physiol
The Biochemical Journal
Diabetologia
Faseb Journal
Am J Physiol Endocrinol Metab
The Journal of Biological Chemistry
Molecular and Cellular Biology
The Journal of Clinical Endocrinology and Metabolism
Obesity (Silver Spring)
Plos Genet
Am J Physiol Regul Integr Comp Physiol
The New England Journal of Medicine
The Journal of Clinical Endocrinology and Metabolism
Faseb Journal
Biochimica Et Biophysica Acta
The Journal of Biological Chemistry
Gerontologist
The Journal of Biological Chemistry
Mol Endocrinol
Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology
Omics: a Journal of Integrative Biology
Proc Natl Acad Sci U S A
Faseb Journal
Nat Rev Mol Cell Biol
Cell Metabolism
Nat Rev Mol Cell Biol
Novartis Foundation Symposium
Novartis Foundation Symposium
Novartis Foundation Symposium
Novartis Foundation Symposium
Novartis Foundation Symposium
Novartis Foundation Symposium
Novartis Foundation Symposium
Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme
American Journal of Physiology. Cell Physiology
Novartis Foundation Symposium
Molecular Cell
Annual Review of Biochemistry
Cell Metabolism
The Journal of Biological Chemistry
The Journal of Biological Chemistry
American Journal of Physiology. Cell Physiology
Medicine and Science in Sports and Exercise
Nature Medicine
Best Practice & Research Clinical Endocrinology & Metabolism
The Journal of Biological Chemistry
American Journal of Physiology. Endocrinology and Metabolism
American Journal of Physiology. Endocrinology and Metabolism
The Japanese Journal of Physiology
The Journal of Biological Chemistry
Annual Review of Nutrition
American Journal of Physiology. Endocrinology and Metabolism
The American Journal of Physiology
The Biochemical Journal
American Journal of Clinical Nutrition
The Journal of Nutritional Biochemistry
Medicine and Science in Sports and Exercise
Medicine and Science in Sports and Exercise
Faseb Journal
Circulation Research
Cancer Research
Faseb Journal
Obesity (Silver Spring, Md.)
Obesity (Silver Spring, Md.)
Type 2 Diabetes Mellitus
Offices & Contact
Durham, NC
27701 Duke Box 104775
Durham, NC
27710