Kathryn Radabaugh Nightingale
Kathryn Radabaugh Nightingale

Kathryn Nightingale

Theo Pilkington Distinguished Professor of Biomedical Engineering


The goals of our laboratory are to investigate and improve ultrasonic imaging methods for clinically-relevant problems. We do this through theoretical, experimental, and simulation methods. The main focus of our recent work is the development of novel, acoustic radiation force impulse (ARFI)-based elasticity imaging methods to generate images of the mechanical properties of tissue, involving interdisciplinary research in ultrasonics and tissue biomechanics. We have access to the engineering interfaces of several commercial ultrasound systems which allows us to design, rapidly prototype, and experimentally demonstrate custom sequences to explore novel beamforming and imaging concepts. We employ FEM modeling methods to simulate the behavior of tissues during mechanical excitation, and we have integrated these tools with ultrasonic imaging modeling tools to simulate the ARFI imaging process. We maintain strong collaborations with the Duke University Medical Center where we work to translate our technologies to clinical practice. The ARFI imaging technologies we have developed have served as the basis for commercial imaging technologies that are now being used in clinics throughout the world.  We are also studying the risks and benefits of increasing acoustic output energy for specific clinical imaging scenarios, with the goal of improving ultrasonic image quality in the difficult-to-image patient.


Theo Pilkington Distinguished Professor of Biomedical Engineering in the Pratt School of Engineering

2019 Pratt School of Engineering

Professor in the Department of Biomedical Engineering in the Pratt School of Engineering

2016 Pratt School of Engineering

Member of the Duke Cancer Institute in the School of Medicine

2016 School of Medicine

Bass Fellow in the Pratt School of Engineering

2018 Pratt School of Engineering


B.S. 1989

1989 Duke University

Ph.D. 1997

1997 Duke University

Publications, Grants & Awards

Offices & Contact

277 Hudson Hall Annex
Durham, NC
Box 90281
Durham, NC