Laura Wingler
Assistant Professor of Pharmacology and Cancer Biology
Overview
Visit our lab website for additional information.
Certain ligands can selectively activate some of the multiple cellular responses downstream of G protein-coupled receptors (GPCRs), an enormous family of membrane proteins that is also the single largest class of drug targets. The Wingler lab seeks to understand the molecular mechanisms of how these ligands differentially modulate GPCR signaling. To accomplish this, the laboratory utilizes multidisciplinary approaches, including biochemistry, biophysics, pharmacology, cell biology and protein engineering. Ultimately, this work could inspire strategies to develop therapeutics for GPCRs that have greater specificity of action.
Positions
Assistant Professor of Pharmacology and Cancer Biology in the School of Medicine
2020 School of Medicine
Assistant Professor of Cell Biology in the School of Medicine
2022 School of Medicine
Member of the Duke Cancer in the School of Medicine
2020 School of Medicine
Education
Ph.D. 2011
2011 Columbia University
Publications, Grants & Awards
- Grants (8)
- Academics Articles (26)
- Conference Pages (7)
Pew Scholars Program
National Institutes of Health
National Institutes of Health
National Institutes of Health
American Society for Pharmacology and Experimental Therapeutics
V Foundation for Cancer Research
American Heart Association
National Institutes of Health
J Cardiovasc Pharmacol
Proc Natl Acad Sci U S A
Science
The Journal of Biological Chemistry
Sci Signal
Mol Pharmacol
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
Mol Pharmacol
Biotechnol J
Acs Medicinal Chemistry Letters
Methods Mol Biol
Proc Natl Acad Sci U S A
ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology
Faseb Journal
Biophysical Journal
Circulation
Abstracts of Papers of the American Chemical Society
Offices & Contact
Durham, NC
27710 C259 LSRC
Durham, NC
27710