Laura M. Wingler
Assistant Professor of Pharmacology and Cancer BiologyOverview
Visit our lab website for additional information.
Certain ligands can selectively activate some of the multiple cellular responses downstream of G protein-coupled receptors (GPCRs), an enormous family of membrane proteins that is also the single largest class of drug targets. The Wingler lab seeks to understand the molecular mechanisms of how these ligands differentially modulate GPCR signaling. To accomplish this, the laboratory utilizes multidisciplinary approaches, including biochemistry, biophysics, pharmacology, cell biology and protein engineering. Ultimately, this work could inspire strategies to develop therapeutics for GPCRs that have greater specificity of action.
Positions
Assistant Professor of Pharmacology and Cancer Biology in the School of Medicine
2020 School of Medicine
Assistant Professor of Cell Biology in the School of Medicine
2022 School of Medicine
Member of the Duke Cancer Institute in the School of Medicine
2020 School of Medicine
Education
Ph.D. 2011
2011 Columbia University
Publications, Grants & Awards
Offices & Contact
Box 3813
Durham, NC
27710
C259 LSRC
Durham, NC
27710