Michael Kastan

William and Jane Shingleton Distinguished Professor of Pharmacology and Cancer Biology
Michael Kastan
Michael Kastan

Overview

Dr. Kastan earned his M.D./Ph.D. from Washington University School of Medicine and did his clinical training in Pediatrics and Pediatric Hematology-Oncology at Johns Hopkins. He was a Professor of Oncology at Johns Hopkins prior to becoming Chair of the Hematology-Oncology Department and later Cancer Center Director at St. Jude Children’s Research Hospital, before moving to Duke in 2011, where he currently serves as the Executive Director of the Duke Cancer Institute and is the William and Jane Shingleton Professor of Pharmacology and Cancer Biology. His laboratory research has focused on cellular responses to DNA damage, including many highly cited publications reporting the roles of p53 and ATM in DNA damage signaling. Among his numerous honors are election to the National Academy of Sciences, National Academy of Medicine, and the American Academy of Arts and Sciences, and receipt of the AACR-G.H.A. Clowes Memorial Award and Failla Award from the Radiation Research Society. He has served as Chair of the Board of Scientific Counselors of the National Cancer Institute (NCI), on the Boards of Directors of the American Association for Cancer Research (AACR) and the American Association of Cancer Institutes (AACI), and as Editor-in-Chief of the journal Molecular Cancer Research. His lab continues to study molecular and biochemical controls of cellular stress responses, particularly those related to DNA damage, and has spun out two companies focused on novel anti-cancer therapeutics.

Positions

William and Jane Shingleton Distinguished Professor of Pharmacology and Cancer Biology in the School of Medicine

2012 School of Medicine

Professor of Pharmacology and Cancer Biology in the School of Medicine

2012 School of Medicine

Director of the Duke Cancer Institute in the School of Medicine

2011 School of Medicine

Professor of Pediatrics in the School of Medicine

2012 School of Medicine

Member of the Duke Cancer Institute in the School of Medicine

2010 School of Medicine

Education

M.D. 1984

1984 Washington University in St. Louis

Ph.D. 1984

1984 Washington University in St. Louis

Publications, Grants & Awards

DCI Centers, Cancer Types & Labs

Offices & Contact

DUMC Box 3917, 10 Bryan Searle Drive, Rm 422
Durham, NC
27710
DUMC Box 3917, 10 Bryan Searle Drive, Rm 422
Durham, NC
27710