Murat Arcasoy
Professor of MedicineOverview
Dr. Arcasoy's research interests include 1)The role of cytokines and cytokine receptors in hematopoietic commitment and lineage-specific differentiation 2) Mechanisms of tissue-specific expression of erythropoietin receptor (EPOR) gene and its role in lineage commitment and lineage-specific differentiation 3) Studies of the molecular basis of familial and congenital myeloproliferative disorders.4). Isolation of novel hematopoietic cytokine-responsive genes and study of their function and regulation 5). Characterization of novel non-hematopoietic functions of EPOR signaling
Dr. Arcasoy's laboratory has been studying the expression, regulation and function of the EPOR gene focusing on the function of naturally occurring mutations of the EPOR gene that result in primary familial and congenital polycythemia as well as the non-hematopoietic expression and functions of EPOR in vascular endothelium, macrophages, cardiac myocytes and cancer cells. We have also been studying global gene expression in erythroid cells from patients with polycythemia vera to better characterize the molecular signature of the disorder and develop new diagnostic tools.
Positions
Professor of Medicine in the School of Medicine
2016 School of Medicine
Member of the Duke Cancer Institute in the School of Medicine
2012 School of Medicine
Education
M.D. 1987
1987 Aegean University, School of Medicine (Turkey)
Medical Resident, Medicine
1991 State University of New York, Brooklyn
Chief Medical Resident, Medicine
1992 State University of New York, Brooklyn
Hematology Fellow, Medicine
1993 Yale University
Fellow in Medical Oncology, Medicine
1998 Yale University
Publications, Grants & Awards
- Grants (9)
- Academics Articles (76)
- Book Sections (1)
Samus Therapeutics, Inc.
Gilead Sciences, Inc.
Janssen Research & Development, LLC
National Institutes of Health
National Institutes of Health
National Institutes of Health
Bone Marrow Transplant
Clin Lymphoma Myeloma Leuk
Advances in Radiation Oncology
Eur J Haematol
Journal of Hematology & Oncology
Open Forum Infectious Diseases
Biol Blood Marrow Transplant
J Natl Compr Canc Netw
Haematologica
Haematologica the Hematology Journal
The New England Journal of Medicine
Bmc Nephrology
Exp Cell Res
Journal of Clinical Oncology
Haematologica
Am J Med
Biochemical and Biophysical Research Communications
Molecular and Cellular Biology
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
Journal of Thrombosis and Thrombolysis
Journal of Clinical Oncology
British Journal of Haematology
Biochemical and Biophysical Research Communications
Molecular Cancer Therapeutics
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology
British Journal of Haematology
Biochimica Et Biophysica Acta
Experimental Hematology
Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc
American Journal of Hematology
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
The American Journal of Medicine
Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology
The American Journal of Medicine
The American Journal of Pathology
Biochemical and Biophysical Research Communications
Laboratory Investigation
Blood
Bulletin of Experimental Biology and Medicine
European Journal of Haematology
Transactions of the American Clinical and Climatological Association
Seminars in Hematology
Experimental Hematology
Molecular and Cellular Biology
Seminars in Perinatology
The Journal of Biological Chemistry
Biological Psychiatry
Anemia: Pathophysiology, Diagnosis, and Management
Offices & Contact
Durham, NC
27710 Hosp South Trent Drive, Box 3912 DUMC
Durham, NC
27710