Pei Zhou

Professor of Biochemistry
Pei Zhou
Pei Zhou

Overview

Protein-protein interactions play a pivotal role in the regulation of various cellular processes. The formation of higher order protein complexes is frequently accompanied by extensive structural remodeling of the individual components, varying from domain re-orientation to induced folding of unstructured elements. Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful tool for macromolecular structure determination in solution. It has the unique advantage of being capable of elucidating the dynamic behavior of proteins during the process of recognition. Recent advances in NMR techniques have enabled the study of significantly larger proteins and protein complexes. These innovations have also led to faster and more accurate structure determination. My research interests focus on the exploration of molecular recognition and conformation variability of protein complexes in crucial biomedical processes using state-of-the-art NMR techniques.

Positions

Professor of Biochemistry in the School of Medicine

2015 School of Medicine

Professor of Chemistry in the Trinity College of Arts & Sciences

2015 Trinity College of Arts & Sciences

Member of the Duke Cancer Institute in the School of Medicine

2001 School of Medicine

Education

Ph.D. 1998

1998 Harvard University

Post-Doct Fellow, Biological Chemistry

2001 Harvard University

Publications, Grants & Awards

Offices & Contact

270 Sands Building, Research Drive
Durham, NC
27710
Duke Box 3711
Durham, NC
27710