
Robert Frank Spurney
Professor of MedicineOverview
Dr. Spurney’s research has focused on the role of G protein coupled receptors (GPCRs) in regulating cellular physiology both in normal and disease states as well as the regulatory mechanisms that modulate GPCR responsiveness at the molecular level. These studies have centered on two major themes. The first investigates the role of GPCR signaling pathways in regulating podocyte function using cultured podocytes and transgenic animals models. The second area of research involves the role of GPCR kinases (GRKs) and arrestin scaffolding proteins in modulating GPCR signaling in bone forming osteoblasts using cultured osteoblast cell lines as well as genetically modified mice including transgenic models and knockout animals. The long-term goal of these studies is to identify novel therapeutic targets that may useful for treating disease processes such as glomerulonephritis and osteoporosis.
Please see the Duke Nephrology Division website for more detailed information.
Positions
Professor of Medicine in the School of Medicine
2012 School of Medicine
Member of the Duke Cancer Institute in the School of Medicine
1983 School of Medicine
Education
M.D., Ohio State University 1983
1983 Ohio State University
Medical Resident, Duke University, Medicine 1983 - 1985
1985 Duke University
Resident in Pathology, Duke University, Pathology 1985 - 1986
1986 Duke University
Senior Assistant Resident, Duke University, Medicine 1986 - 1987
1987 Duke University
Fellow in Nephrology, Duke University, Medicine 1987 - 1990
1990 Duke University
Publications, Grants & Awards
Offices & Contact
Durham, NC
27710
Durham, NC
27710