Simon Gray Gregory
Simon Gray Gregory

Simon Gray Gregory

Margaret Harris and David Silverman Distinguished Professor

Overview

Dr. Gregory is the Margaret Harris and David Silverman Distinguished Professor and Director of the Brain Tumor Omics Program in the Duke Department of Neurosurgery, the Vice Chair of Research in the Department of Neurology, and Director of the Molecular Genomics Core at the Duke Molecular Physiology Institute. 

As a neurogenomicist, Dr. Gregory applies the experience gained from leading the sequencing of chromosome 1 for the Human Genome Project to elucidating the mechanisms underlying multi-factorial diseases using genetic, genomic, and epigenetic approaches. Dr. Gregory’s primary areas of research involve understanding the molecular processes associated with disease development and progression in brain tumors and Alzheimer’s disease, drug induced white matter injury repair in multiple sclerosis, and the characterization of lesion microenvironmental changes in MS.

He is broadly regarded across Duke as a leader in the development of novel single cell and spatial molecular technologies towards understanding the pathogenic mechanisms of disease development. Dr. Gregory is also the Section Chair of Genomics and Epigenetics at the DMPI and Director of the Duke Center of Autoimmunity and MS in the Department of Neurology.

Positions

Margaret Harris and David Silverman Distinguished Professor in the School of Medicine

2024 School of Medicine

Professor in Neurosurgery in the School of Medicine

2022 School of Medicine

Vice Chair for Research in the Department of Neurology in the School of Medicine

2020 School of Medicine

Professor in Neurology in the School of Medicine

2022 School of Medicine

Professor in Molecular Genetics and Microbiology in the School of Medicine

2021 School of Medicine

Member of Duke Molecular Physiology Institute in the School of Medicine

2013 School of Medicine

Member of the Duke Cancer Institute in the School of Medicine

2003 School of Medicine

Education

B.A.Sc. 1990

1990 RMIT University (Australia)

Ph.D. 2003

2003 Open University, Milton Keynes (United Kingdom)

Publications, Grants & Awards

DCI Centers, Cancer Types & Labs

Offices & Contact

300 N. Duke Street, Room 51-102
Durham, NC
27701
Duke Box 104775
Durham, NC
27701