Vidyalakshmi Chandramohan
Associate Professor in Neurosurgery
Overview
The research work in my laboratory focuses on identifying novel immunotherapeutic targets for the treatment of brain tumors, specifically glioblastoma (GBM). My previous work includes the development of the dual-specific immunotoxin (IT) D2C7-IT, which is currently in Phase I clinical trials in recurrent GBM (rGBM) patients. My current research seeks to identify novel strategies to enhance the efficacy of D2C7-IT and other GBM-targeted cytotoxic therapies. In conjunction with this, my research includes the investigation of immune-related biomarkers to predict the clinical outcome of D2C7-IT therapy in patients with GBM.
Positions
Associate Professor in Neurosurgery in the School of Medicine
2021 School of Medicine
Associate Professor in Pathology in the School of Medicine
2020 School of Medicine
Member of the Duke Cancer Institute in the School of Medicine
2015 School of Medicine
Education
Ph.D. 2006
2006 Boston University
M.B.A. 2020
2020 North Carolina State University
Postdoctoral Associate, Surgery
2007 Duke University School of Medicine
Research Associate, Pathology
2010 Duke University School of Medicine
Research Associate, Sr, Pathology
2012 Duke University School of Medicine
Publications, Grants & Awards
- Grants (12)
- Academics Articles (32)
- Conference Pages (36)
- Book Sections (2)
National Institutes of Health
National Institutes of Health
Brain Tumor Research Charity
Brain Tumor Research Charity
Jewish Communal Fund
Brain Tumor Research Charity
National Institutes of Health
National Institutes of Health
Uncle Kory Foundation
Brain Tumor Research Charity
Uncle Kory Foundation
Uncle Kory Foundation
Cell Death & Disease
Acta Neuropathologica Communications
Sci Transl Med
Journal for Immunotherapy of Cancer
Plos One
Clinical Cancer Research
J Neuropathol Exp Neurol
Arch Pathol Lab Med
Sci Transl Med
Protein Engineering, Design and Selection
Appl Microbiol Biotechnol
J Immunol Methods
Invest New Drugs
Cancer Immunol Res
Oncoimmunology
Oncoimmunology
Clinical Cancer Research
Int J Cancer
Clin Dev Immunol
Nucl Med Biol
Biochemical and Biophysical Research Communications
Journal of Cellular Biochemistry
Neuro Oncology
The Journal of Immunology
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Oncology Research and Treatment
Frontiers in Immunology
Neuro Oncology
Annals of Surgical Oncology
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Neuro Oncology
Neuro Oncology
Neuro Oncology
Cancer Immunology Research
Journal for Immunotherapy of Cancer
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
American Journal of Respiratory and Critical Care Medicine
Cancer Immunology Research
Neuro Oncology
Translational Immunotherapy of Brain Tumors
Translational Immunotherapy of Brain Tumors
Offices & Contact
Durham, NC
27710 Box 3156 Med Ctr
Durham, NC
27710