Headshot of Carolyn Coyne
Carolyn Coyne

Carolyn Coyne

George Barth Geller Distinguished Professor of Immunology

Overview

We study the pathways by which microorganisms cross cellular barriers and the mechanisms by which these barriers restrict microbial infections. Our studies primarily focus on the epithelium that lines the gastrointestinal tract and on placental trophoblasts, the cells that comprise a key cellular barrier of the human placenta. Our work is highly multidisciplinary and encompasses aspects of cell biology, immunology, and microbiology. Our long-term goals are to identify pathogen- and host-specific therapeutic targets to prevent or treat microbial infections and ultimately to alleviate the morbidity and mortality caused by these infections.

Positions

George Barth Geller Distinguished Professor of Immunology in the School of Medicine

2022 School of Medicine

Professor of Integrative Immunobiology in the School of Medicine

2023 School of Medicine

Professor of Molecular Genetics and Microbiology in the School of Medicine

2025 School of Medicine

Professor of Cell Biology in the School of Medicine

2022 School of Medicine

Professor of Pathology in the School of Medicine

2022 School of Medicine

Member of the Duke Cancer Institute in the School of Medicine

2021 School of Medicine

Member in the Duke Human Vaccine Institute in the School of Medicine

2021 School of Medicine

Education

Ph.D., University of North Carolina, Chapel Hill 2003

2003 University of North Carolina, Chapel Hill

Publications, Grants & Awards

Showing 1 - 5 of 21
Model Systems Core (MODS Core)

Weill Cornell Medicine

Interferon-inducible cell-intrinsic host defense against Chlamydia trachomatis

National Institute of Allergy and Infectious Diseases

Design and testing picornavirus vaccine candidates

Vanderbilt University Medical Center

Microbial regulation of intestinal epithelial gene expression

National Institute of Diabetes and Digestive and Kidney Diseases

Control of virus induced type I interferon signaling during pregnancy

National Institute of Allergy and Infectious Diseases

Offices & Contact

Address Icon 3130 MSRB III BX 3054
Durham, NC
27710
Address Icon 3130 MSRB III
Durham, NC
27710