Karl-Dimiter Bissig
Chen Family Associate Professor of PediatricsOverview
Our group is interested in diseases of the liver, ranging from viral hepatitis to metabolic liver disorders and liver cancer. The lab specializes in human liver chimeric mice and created the first xenograft model for metabolic liver disease as well as a novel patient derived cancer model. We use these next generation humanized mouse models to develop new therapeutic approaches, such as metabolic pathway reprogramming - a CRISPR based gene therapy approach.
Positions
Chen Family Associate Professor of Pediatrics in the School of Medicine
2022 School of Medicine
Associate Professor in Pediatrics in the School of Medicine
2021 School of Medicine
Associate Professor of Biomedical Engineering in the Pratt School of Engineering
2022 Pratt School of Engineering
Associate Professor in Pharmacology and Cancer Biology in the School of Medicine
2021 School of Medicine
Affiliate of the Duke Regeneration Center in the School of Medicine
2021 School of Medicine
Member of the Duke Cancer Institute in the School of Medicine
2019 School of Medicine
Education
MD./PhD. 2000
2000 Universitat Bern (Switzerland)
Residency, INTERNAL MEDICINE
2005 Inselspital (Switzerland)
Postdoctoral Fellow
2011 Salk Institute for Biological Studies